In the present scenario, immunization is of utmost importance as it keeps us safe and
protects us from infectious agents. Despite the great success in the field of vaccinology …

Vaccines are the most effective and cost-efficient method for preventing diseases caused by
infectious pathogens. Despite the great success of vaccines, development of safe and strong …

New generation vaccines will increasingly comprise highly purified recombinant proteins.
Unfortunately, these antigens are often poorly immunogenic. Therefore, adjuvants will be …

Vaccines represent the most efficient tool for preventing diseases caused by infectious
pathogens. During the last century significant progress has been made in vaccine …

Vaccines containing novel adjuvant formulations are increasingly reaching advanced
development and licensing stages, providing new tools to fill previously unmet clinical …

Although there are only four adjuvants used in licensed vaccines for humans, a wealth of
information on novel vaccine adjuvants has become available in both animal models and …

The majority of vaccine antigens currently under investigation represent recombinant
molecules or subunits of pathogens with little or no inherent immunostimulatory property …

Highlights•New adjuvants are typically a combination of delivery system and an immune
potentiator.•A deeper understanding of innate immunity has helped the discovery of new …

In the last decade there have been some significant advances in vaccine adjuvants,
particularly in relation to their inclusion in licensed products. This was proceeded by several …

Mucosal vaccination, capable of inducing protective immune responses both in the mucosal
and systemic immune compartments, has many advantages and is regarded as a blue …