Salivary and plasmatic oxytocin are not reliable trait markers of the physiology of the oxytocin system in humans

D Martins, AS Gabay, M Mehta, Y Paloyelis - Elife, 2020 - elifesciences.org
Single measurements of salivary and plasmatic oxytocin are used as indicators of the
physiology of the oxytocin system. However, questions remain about whether they are …

[PDF][PDF] Salivary levels of oxytocin remain elevated for more than two hours after intranasal oxytocin administration

R Huffmeijer, LRA Alink, M Tops, KM Grewen… - Neuroendocrinol …, 2012 - nel.altamira.sk
OBJECTIVE: This is the first study investigating whether levels of oxytocin in saliva remained
elevated after intranasal oxytocin administration for the duration of an experiment (in which …

Saliva oxytocin measures do not reflect peripheral plasma concentrations after intranasal oxytocin administration in men

DS Quintana, LT Westlye, KT Smerud… - Hormones and …, 2018 - Elsevier
Oxytocin plays an important role in social behavior. Thus, there has been significant
research interest for the role of the oxytocin system in several psychiatric disorders, and the …

Elevated salivary levels of oxytocin persist more than 7 h after intranasal administration

MH Van IJzendoorn, R Bhandari… - Frontiers in …, 2012 - frontiersin.org
We addressed the question how long salivary oxytocin levels remain elevated after
intranasal administration, and whether it makes a difference when 16 or 24 IU of oxytocin …

Salivary oxytocin concentrations in males following intranasal administration of oxytocin: a double-blind, cross-over study

K Daughters, ASR Manstead, K Hubble, A Rees… - PLOS …, 2015 - journals.plos.org
The use of intranasal oxytocin (OT) in research has become increasingly important over the
past decade. Although researchers have acknowledged a need for further investigation of …

Oxytocin is not a valid biomarker when measured in saliva by immunoassay

M Horvat-Gordon, DA Granger, EB Schwartz… - Physiology & …, 2005 - Elsevier
The integration of oxytocin (OT) into behavioral science seems to hold considerable promise
for advancing our understanding of human health and development but methodological …

Oxytocin plasma concentrations after single intranasal oxytocin administration–a study in healthy men

A Gossen, A Hahn, L Westphal, S Prinz, RT Schultz… - Neuropeptides, 2012 - Elsevier
The neuropeptide oxytocin has become a subject of great interest in studies investigating
human social cognition. Single intranasal administration of the hormone has been reported …

Oxytocin: behavioral associations and potential as a salivary biomarker

C Sue Carter… - Annals of the new …, 2007 - Wiley Online Library
Oxytocin (OT) is a neuropeptide that is produced primarily in the hypothalamus and is best
known for its role in mammalian birth and lactation. Recent evidence also implicates OT in …

Challenges for measuring oxytocin: The blind men and the elephant?

EL MacLean, SR Wilson, WL Martin, JM Davis… - …, 2019 - Elsevier
Since its discovery more than a century ago, oxytocin has become one of the most
intensively studied molecules in behavioral biology. In the last five years …

The correlation between central and peripheral oxytocin concentrations: a systematic review and meta-analysis

M Valstad, GA Alvares, M Egknud… - Neuroscience & …, 2017 - Elsevier
There is growing interest in the role of the oxytocin system in social cognition and behavior.
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …