Randomized trials of therapeutic heparin for COVID‐19: a meta‐analysis

M Sholzberg, BR da Costa, GH Tang… - … and practice in …, 2021 - Wiley Online Library
Background Pulmonary endothelial injury and microcirculatory thromboses likely contribute
to hypoxemic respiratory failure, the most common cause of death, in patients with COVID …

[HTML][HTML] Heparin in COVID-19 patients is associated with reduced in-hospital mortality: the multicenter Italian CORIST study

A Di Castelnuovo, S Costanzo… - Thrombosis and …, 2021 - thieme-connect.com
Introduction A hypercoagulable condition was described in patients with coronavirus
disease 2019 (COVID-19) and proposed as a possible pathogenic mechanism contributing …

[HTML][HTML] The association between treatment with heparin and survival in patients with Covid-19

L Ayerbe, C Risco, S Ayis - Journal of thrombosis and thrombolysis, 2020 - Springer
This study investigates the association between the treatment with heparin and mortality in
patients admitted with Covid-19. Routinely recorded, clinical data, up to the 24th of April …

Heparin for moderately ill patients with Covid-19

M Sholzberg, GH Tang, H Rahhal, M AlHamzah… - medRxiv, 2021 - medrxiv.org
Background Heparin, in addition to its anticoagulant properties, has anti-inflammatory and
potential anti-viral effects, and may improve endothelial function in patients with Covid-19 …

Heterogeneous treatment effects of therapeutic-dose heparin in patients hospitalized for COVID-19

EC Goligher, PR Lawler, TP Jensen, V Talisa, LR Berry… - Jama, 2023 - jamanetwork.com
Importance Randomized clinical trials (RCTs) of therapeutic-dose heparin in patients
hospitalized with COVID-19 produced conflicting results, possibly due to heterogeneity of …

Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid …

M Sholzberg, GH Tang, H Rahhal, M AlHamzah… - bmj, 2021 - bmj.com
Objective To evaluate the effects of therapeutic heparin compared with prophylactic heparin
among moderately ill patients with covid-19 admitted to hospital wards. Design Randomised …

[HTML][HTML] The potential role of heparin in patients with COVID-19: beyond the anticoagulant effect. A review

L Gozzo, P Viale, L Longo, DC Vitale… - Frontiers in …, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is responsible of
variable clinical manifestations, ranging from no symptoms to severe pneumonia with acute …

[HTML][HTML] Clinical outcome with different doses of low-molecular-weight heparin in patients hospitalized for COVID-19

MG Mennuni, G Renda, L Grisafi, A Rognoni… - Journal of thrombosis …, 2021 - Springer
A pro-thrombotic milieu and a higher risk of thrombotic events were observed in patients with
CoronaVirus disease-19 (COVID-19). Accordingly, recent data suggested a beneficial role of …

[HTML][HTML] Preliminary experience with low molecular weight heparin strategy in COVID-19 patients

P Paolisso, L Bergamaschi, EC D'Angelo… - Frontiers in …, 2020 - frontiersin.org
Background Heparin administration in COVID-19 patients is recommended by expert
consensus, although evidence about dosage, duration and efficacy are limited. We aim to …

[HTML][HTML] A systematic review and a meta-analysis comparing prophylactic and therapeutic low molecular weight heparins for mortality reduction in 32,688 COVID-19 …

R Giossi, D Menichelli, A Pani, E Tratta… - Frontiers in …, 2021 - frontiersin.org
Background: Antithrombotic treatment, including low molecular weight heparin (LMWH) or
unfractionated heparin (UFH), has been proposed as a potential therapy for coronavirus …