[PDF][PDF] MAIT cells are enriched and highly functional in ascites of patients with decompensated liver cirrhosis
Background and Aims Patients with advanced liver cirrhosis have an increased
susceptibility to infections. As part of the cirrhosis‐associated immune dysfunction, mucosal …
susceptibility to infections. As part of the cirrhosis‐associated immune dysfunction, mucosal …
[HTML][HTML] Mucosal-associated invariant T cells redistribute to the peritoneal cavity during spontaneous bacterial peritonitis and contribute to peritoneal inflammation
O Ibidapo-Obe, S Stengel, N Köse-Vogel… - Cellular and molecular …, 2020 - Elsevier
Background & Aims Mucosal-associated invariant T (MAIT) cells are depleted from blood in
patients with advanced liver disease and show features of immune dysfunction. Because …
patients with advanced liver disease and show features of immune dysfunction. Because …
Modeling the hepatology workforce in the United States: a predicted critical shortage
MW Russo, OK Fix, AA Koteish, K Duggan… - Hepatology, 2020 - journals.lww.com
Conclusions Despite severely diminished MAIT cell numbers and impaired phenotype in
circulation, peritoneal MAIT cells remain abundant, activated, and highly functional in …
circulation, peritoneal MAIT cells remain abundant, activated, and highly functional in …
MAIT cells: new guardians of the liver
A Kurioka, LJ Walker, P Klenerman… - Clinical & translational …, 2016 - Wiley Online Library
The liver is an important immunological organ that remains sterile and tolerogenic in
homeostasis, despite continual exposure to non‐self food and microbial‐derived products …
homeostasis, despite continual exposure to non‐self food and microbial‐derived products …
Mucosal-associated invariant T cells in chronic inflammatory liver disease
FJ Bolte, B Rehermann - Seminars in liver disease, 2018 - thieme-connect.com
The broadening field of microbiome research has led to a substantial reappraisal of the gut–
liver axis and its role in chronic liver disease. The liver is a central immunologic organ that is …
liver axis and its role in chronic liver disease. The liver is a central immunologic organ that is …
[HTML][HTML] Mucosal-associated invariant T cells in hepatitis B virus-related liver failure
H Xue, H Li, LL Ju, XD Han, TC Cheng… - World journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Liver failure has high mortality and poor prognosis, and establishing new
reliable markers for predicting its prognosis is necessary. Mucosal-associated invariant T …
reliable markers for predicting its prognosis is necessary. Mucosal-associated invariant T …
MAIT cells in liver inflammation and fibrosis
H Mehta, MJ Lett, P Klenerman… - Seminars in …, 2022 - Springer
Mucosal-associated invariant T cells or MAIT cells are an abundant cell type in humans and
especially so in the liver. MAIT cells are a subset of T lymphocytes that sit at a bridge …
especially so in the liver. MAIT cells are a subset of T lymphocytes that sit at a bridge …
[PDF][PDF] MAIT cells are chronically activated in patients with autoimmune liver disease and promote profibrogenic hepatic stellate cell activation
K Böttcher, K Rombouts, F Saffioti, D Roccarina… - …, 2018 - Wiley Online Library
Autoimmune liver diseases (AILDs) are chronic liver pathologies characterized by fibrosis
and cirrhosis due to immune‐mediated liver damage. In this study, we addressed the …
and cirrhosis due to immune‐mediated liver damage. In this study, we addressed the …
Lights on MAIT cells, a new immune player in liver diseases
A Toubal, A Lehuen - Journal of Hepatology, 2016 - journal-of-hepatology.eu
Mucosal associated invariant T (MAIT) cells are a recently identified subset of invariant T
cells. They express a conserved invariant T cell antigen receptor (TCR) a-chain, composed …
cells. They express a conserved invariant T cell antigen receptor (TCR) a-chain, composed …
Persistent deficiency of mucosa-associated invariant T (MAIT) cells during alcohol-related liver disease
Background Alcohol-related liver disease (ALD) is a major cause of chronic liver diseases.
Inflammatory response is a basic pathological feature of ALD. Mucosal-associated invariant …
Inflammatory response is a basic pathological feature of ALD. Mucosal-associated invariant …