Fermented Lettuce Extract Containing Nitric Oxide Metabolites Attenuates Inflammatory Parameters in Model Mice and in Human Fibroblast-Like Synoviocytes

J Park, JH Ryu, BY Kim, HS Chun, MS Kim, YI Shin - Nutrients, 2023 - mdpi.com
Lettuce (Lactuca sativa L.) contains various bioactive compounds that can reduce the
severity of inflammatory diseases. This study aimed to identify therapeutic effects and …

[HTML][HTML] Therapeutic Effects of Gleditsia sinensis Thorn Extract Fermented by Lactobacillus casei 3260 in a Type II Collagen-Induced Rheumatoid Arthritis Mouse …

JY Eor, N Park, YJ Son, SH Kim - Food science of animal resources, 2021 - ncbi.nlm.nih.gov
This study aimed to assess the anti-inflammatory effect of Lactobacillus casei 3260 (LC)
alone and LC-fermented Gleditsia sinensis thorn (GST) extract in mouse model of type II …

A herbal formula comprising Rosae Multiflorae Fructus and Lonicerae Japonicae Flos, attenuates collagen-induced arthritis and inhibits TLR4 signalling in rats

BCY Cheng, H Yu, H Guo, T Su, XQ Fu, T Li, HH Cao… - Scientific Reports, 2016 - nature.com
RL, a traditional remedy for Rheumatoid arthritis (RA), comprises two edible herbs, Rosae
Multiflorae Fructus and Lonicerae Japonicae Flos. We have reported that RL could inhibit …

Lonicerin alleviates the progression of experimental rheumatoid arthritis by downregulating M1 macrophages through the NF‐κB signaling pathway

X Yang, H Qian, J Meng, H Jiang, T Yuan… - Phytotherapy …, 2023 - Wiley Online Library
The present study aimed to evaluate anti‐rheumatoid arthritis (RA) effect of Lonicerin (LON),
a safe compound with anti‐inflammatory and immunomodulatory properties. Nevertheless …

Citrus peel flavonoid nobiletin alleviates lipopolysaccharide-induced inflammation by activating IL-6/STAT3/FOXO3a-mediated autophagy

X Rong, J Xu, Y Jiang, F Li, Y Chen, QP Dou, D Li - Food & function, 2021 - pubs.rsc.org
Nobiletin, a polymethoxyflavone widely present in the peel of citrus fruits, has significant anti-
inflammatory activity. Autophagy plays a critical role in maintaining cell homeostasis by …

Puerarin attenuates inflammation and oxidation in mice with collagen antibody-induced arthritis via TLR4/NF-κB signaling

C Wang, W Wang, X Jin, J Shen… - Molecular Medicine …, 2016 - spandidos-publications.com
Puerarin is an important active ingredient in the root of kudzu vine due to its
pharmacological properties. The aim of the present study is to contribute to the existing …

Herbal Formula Longteng Decoction Promotes the Regression of Synovial Inflammation in Collagen-Induced Arthritis Mice by Regulating Type 2 Innate Lymphocytes

H Zhang, J Liu, P Zhang, D Li, G Feng… - Frontiers in …, 2021 - frontiersin.org
The etiology and pathogenesis of rheumatoid arthritis (RA) have not yet been fully
elucidated, with greater adverse drug effects in traditional treatment of RA. It is particularly …

Ferulic acid exhibits anti-inflammatory effects by inducing autophagy and blocking NLRP3 inflammasome activation

Y Liu, L Shi, W Qiu, Y Shi - Molecular & cellular toxicology, 2022 - Springer
Background Inflammation is involved in the healing process; however, when inflammation is
overactivated, multiple diseases can occur. The continued discovery of new anti …

Resveratrol alleviates rheumatoid arthritis via reducing ROS and inflammation, inhibiting MAPK signaling pathways, and suppressing angiogenesis

G Yang, CC Chang, Y Yang, L Yuan, L Xu… - Journal of agricultural …, 2018 - ACS Publications
Rheumatoid arthritis (RA) is a systemic autoimmune disease primarily affecting joints and is
featured by chronic synovial inflammation and angiogenesis. We employed a bovine type-II …

Carnosic acid inhibits inflammation response and joint destruction on osteoclasts, fibroblast‐like synoviocytes, and collagen‐induced arthritis rats

M Liu, X Zhou, L Zhou, Z Liu, J Yuan… - Journal of cellular …, 2018 - Wiley Online Library
The discovery of new therapeutic drugs with the ability of preventing inflammation and joint
destruction with less adverse effects is urgently needed for rheumatoid arthritis (RA) …