A high concentrate diet inhibits forkhead box protein A2 expression, and induces oxidative stress, mitochondrial dysfunction and mitochondrial unfolded protein …
RK Zuo, C Wang, ZY Yu, HM Shi, XK Song… - Microbial …, 2024 - Elsevier
High-concentrate diet induce subacute ruminal acidosis (SARA) and cause liver damage in
ruminants. It has been reported that forkhead box protein A2 (FOXA2) can enhance …
ruminants. It has been reported that forkhead box protein A2 (FOXA2) can enhance …
[HTML][HTML] Subacute ruminal acidosis downregulates FOXA2, changes oxidative status, and induces autophagy in the livers of dairy cows fed a high-concentrate diet
H Zhang, Y Xue, W Xie, Y Wang, N Ma, G Chang… - Journal of Dairy …, 2023 - Elsevier
The purpose of this experiment was to investigate high-concentrate feeding-induced
changed status of oxidative and autophagy in the livers of dairy cows. Hepatocyte nuclear …
changed status of oxidative and autophagy in the livers of dairy cows. Hepatocyte nuclear …
[HTML][HTML] Forkhead box protein A2 alleviates toll-like receptor 4-mediated inflammation, endoplasmic reticulum stress, autophagy, and apoptosis induced by …
W Xie, Y Xue, X Song, H Zhang, G Chang… - Journal of Dairy Science, 2023 - Elsevier
Lipopolysaccharide (LPS) is an important stimulus of inflammation via binding to toll-like
receptor 4 (TLR4), but the role of TLR4 in LPS-induced cellular homeostasis disruption …
receptor 4 (TLR4), but the role of TLR4 in LPS-induced cellular homeostasis disruption …
A high-concentrate diet provokes inflammatory responses by downregulating Forkhead box protein A2 (FOXA2) through epigenetic modifications in the liver of dairy …
W Xie, Y Xue, H Zhang, Y Wang, M Meng, G Chang… - Gene, 2022 - Elsevier
A high-concentrate diet has been reported to promote an inflammatory response in dairy
cows. The purpose of this study was to clarify the effect of the high-concentrate (HC) diet on …
cows. The purpose of this study was to clarify the effect of the high-concentrate (HC) diet on …
[HTML][HTML] Low abundance of mitophagy markers is associated with reactive oxygen species overproduction in cows with fatty liver and causes reactive oxygen species …
Mitochondria are the main site of fatty acid oxidation and reactive oxygen species (ROS)
formation. Damaged or dysfunctional mitochondria induce oxidative stress and increase the …
formation. Damaged or dysfunctional mitochondria induce oxidative stress and increase the …
[HTML][HTML] AMPK-endoplasmic reticulum stress axis contributes to lipopolysaccharide-caused mitochondrial dysfunction by regulating mitochondria-associated …
W Xie, M Chen, JJ Loor, X Song, N Ma, S Zhou… - Journal of Dairy …, 2023 - Elsevier
Mitochondrial homeostasis is closely associated with cellular homeostasis process, whereas
mitochondrial dysfunction contributes to apoptosis and mitophagy. Hence, analyzing the …
mitochondrial dysfunction contributes to apoptosis and mitophagy. Hence, analyzing the …
Effects of high-grain diet with buffering agent on the hepatic metabolism in lactating goats
M He, L Li, H Wang, S Yan, Y Zhang - Frontiers in Physiology, 2019 - frontiersin.org
To gain insight on the effects of a high-grain diet with buffering agent on liver metabolism
and the changes of plasma biochemical parameters and amino acids in hepatic vein and …
and the changes of plasma biochemical parameters and amino acids in hepatic vein and …
Comparative proteomic analysis of the effects of high-concentrate diet on the hepatic metabolism and inflammatory response in lactating dairy goats
Y Duanmu, R Cong, S Tao, J Tian, H Dong… - Journal of Animal …, 2016 - Springer
Background To understand the impact of feeding a high-concentrate diet to mid-lactating
goats for a long time on liver metabolism and inflammatory response, two dimensional …
goats for a long time on liver metabolism and inflammatory response, two dimensional …
Hepatic transcriptome perturbations in dairy cows fed different forage resources
ST Gao, L Ma, YD Zhang, JQ Wang, JJ Loor, DP Bu - BMC genomics, 2021 - Springer
Background Forage plays critical roles in milk performance of dairy. However, domestic high-
quality forage such as alfalfa hay is far from being sufficient in China. Thus, more than 1 …
quality forage such as alfalfa hay is far from being sufficient in China. Thus, more than 1 …
Long-term high-grain diet alters ruminal pH, fermentation, and epithelial transcriptomes, leading to restored mitochondrial oxidative phosphorylation in Japanese …
T Ogata, H Makino, N Ishizuka, E Iwamoto, T Masaki… - Scientific Reports, 2020 - nature.com
To increase intramuscular fat accumulation, Japanese Black beef cattle are commonly fed a
high-grain diet from 10 to 30 months of age. Castrated and fistulated cattle (n= 9) were fed a …
high-grain diet from 10 to 30 months of age. Castrated and fistulated cattle (n= 9) were fed a …
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