BACKGROUND & AIMS: Age-related inflammation and insulin resistance (IR) have been
implicated in the inability of old muscles to properly respond to anabolic stimuli such as …

Age-related sarcopenia is associated with a variety of changes in skeletal muscle. These
changes are interrelated with each other and associated with systemic metabolism, the …

Aging is associated with increased visceral adiposity and a decrease in the amount of brown
adipose tissue and muscle mass, known as sarcopenia, which results in the development of …

Skeletal muscle mitochondrial dysfunction is associated with aging and diabetes, which
decreases respiratory capacity and increases reactive oxygen species. Lipoic acid (LA) …

Obesity and aging promote chronic low-grade systemic inflammation. The aim of the study
was to analyze the effects of long-term physical exercise and/or omega-3 fatty acid …

Objectives Skeletal muscle mitochondrial dysfunction is associated with aging and diabetes,
which decreases respiratory capacity and increases reactive oxygen species. Lipoic acid …

Obesity and inflammation are reportedly associated with the pathogenesis of sarcopenia,
which is characterized by age‐related loss of skeletal muscle mass. Intramuscular fat …

Leucine acts as a signal nutrient in promoting protein synthesis in skeletal muscle and
adipose tissue via mTOR pathway activation, and may be of interest in age-related …

Objective The aim of this study was to evaluate the effects of long-term energy restriction
(ER) on plasma, liver, and skeletal muscle metabolite profiles in aging rats fed a Western …

Introduction Nutritional support is potentially considered an essential step to prevent muscle
loss and enhance physical function in older adults. Objectives This study aimed to assess …