Background Chronic heart failure (CHF) has high morbidity and mortality rates despite
treatment with angiotensin-converting enzyme inhibitors, diuretics, and digoxin. Adjunctive …

A considerable effort has been made in the last 15 years to evaluate the safety and efficacy
of calcium channel blockers (CCBs) in the treatment of patients with chronic congestive …

Despite the beneficial effect of vasodilator therapy on symptoms and survival of patients with
chronic heart failure, the mortality and morbidity of these patients remains high. One …

Congestive cardiac failure is an increasingly prevalent syndrome associated with a high
morbidity and mortality. The role of calcium channel blockers in the treatment of heart failure …

The rationale for the use of calcium enamel bleckers in patients with chronic heart failure lies
in their vasodilator action, antiischemic effect, ability to lessen left ventricular diastole …

Calcium channel blockers are theoretically effective in the treatment of chronic systolic heart
failure because of their actions as arteriolar dilators, antiischemic agents, and relaxants of …

C areful examination of the results of the Mul-ticenter Diltiazem Postinfarction Trial (MDPIT)
by the Adverse Experience Committee and the MDPIT Research Group, reported in this …

The presence of calcium ions is essential to the normal function of the cardiovascular
system. Drugs such as calcium antagonists can modulate the interaction between these ions …

Background Previous studies have shown that calcium-channel blockers increase morbidity
and mortality in patients with chronic heart failure. We studied the effect of a new calcium …

Calcium channel antagonists (CCAs) may either be divided into the dihydropyridines (eg
amlodipine, felodipine, isradipine, lacidipine, nilvadipine, nifedipine, nicardipine etc.), the …