Advances in Simple, Rapid, and Contamination-Free Instantaneous Nucleic Acid Devices for Pathogen Detection

Y Wang, C Wang, Z Zhou, J Si, S Li, Y Zeng, Y Deng… - Biosensors, 2023 - mdpi.com
Pathogenic pathogens invade the human body through various pathways, causing damage
to host cells, tissues, and their functions, ultimately leading to the development of diseases …

Nucleic acid-based detection of bacterial pathogens using integrated microfluidic platform systems

C Lui, NC Cady, CA Batt - Sensors, 2009 - mdpi.com
The advent of nucleic acid-based pathogen detection methods offers increased sensitivity
and specificity over traditional microbiological techniques, driving the development of …

The latest progress of on-site pathogens detection techniques and instruments based on nucleic acid

H He, Y Wu, N He, Y Deng - Journal of Nanoscience and …, 2015 - ingentaconnect.com
Infectious diseases are a major threat to the survival and development of humanity around
the world. Timely and accurate diagnosis is proved to be an essential prerequisite for the …

[HTML][HTML] Recent developments and trends of automatic nucleic acid detection systems

X Yuan, G Sui, D Zhang, M Chen, W Zhao - Journal of Biosafety and …, 2022 - Elsevier
Nucleic acid detection, widely used in clinical diagnosis, biological analysis, and
environmental monitoring, is of great significance for disease diagnosis and basic research …

Integrated point-of-care molecular diagnostic devices for infectious diseases

W Liu, F Yue, LP Lee - Accounts of chemical research, 2021 - ACS Publications
Conspectus The global outbreaks of deadly infectious diseases caused by pathogenic
microorganisms have threatened public health worldwide and significantly motivated …

Advancements in Biosensors for Point-of-Care Testing of Nucleic Acid

T Ming, T Lan, M Yu, S Cheng, X Duan… - Critical Reviews in …, 2024 - Taylor & Francis
Rapid, low-cost and high-specific diagnosis based on nucleic acid detection is pivotal in
both detecting and controlling various infectious diseases, effectively curbing their spread …

Simple approaches to minimally-instrumented, microfluidic-based point-of-care nucleic acid amplification tests

MG Mauk, J Song, C Liu, HH Bau - Biosensors, 2018 - mdpi.com
Designs and applications of microfluidics-based devices for molecular diagnostics (Nucleic
Acid Amplification Tests, NAATs) in infectious disease testing are reviewed, with emphasis …

Next-generation pathogen detection: Exploring the power of nucleic acid amplification-free biosensors

Y Wang, Z Wang, Y Shang, J Wang, Z Zhu, L Xi… - Coordination Chemistry …, 2024 - Elsevier
Abstract Accurate, rapid, cost-effective, and point-of-care pathogen identification is crucial for
public health safety and encompasses disease prevention, food safety, and environmental …

High-throughput sample-to-answer detection of DNA/RNA in crude samples within functionalized micro-pipette tips

W Lu, J Wang, Q Wu, J Sun, Y Chen, L Zhang… - Biosensors and …, 2016 - Elsevier
We develop a micro-pipette tip-based nucleic acid test (MTNT) for high-throughput sample-
to-answer detection of both DNA and RNA from crude samples including cells, bacteria, and …

Point-of-care molecular diagnostic systems—past, present and future

CA Holland, FL Kiechle - Current opinion in microbiology, 2005 - Elsevier
The field of molecular diagnostics has greatly decreased the time it takes to identify
infectious agents and to test their antimicrobial resistance. Portable devices are currently in …