Alzheimer is an age-dependent neurodegenerative process distinct from normal aging and
characterized morphologically by the presence of senile plaques and neurofibrillary tangles …

The two major neuropathologic hallmarks of Alzheimer''s disease are extracellular amyloid
bβ (Abβ) plaques and intracellular neurofibrillary tangles. Several additional pathogenic …

The underlying pathological cause of Alzheimer's disease has been postulated to be an
excess of amyloid-β (Aβ) which aggregates into toxic fibrillar deposits within the extracellular …

Alzheimer's disease (AD) is the most prevalent form of dementia which affects people older
than 60 years of age. In AD, the dysregulation of the amyloid-beta (Aβ) level leads to the …

Alzheimer's disease (AD), the most common form of senile dementia, is characterized by a
progressive disruption of memory, cognition, functional ability, mood and behavior. At the …

In 1906, the Bavarian physician Alois Alzheimer described the form of progressive senile
dementia that bears his name. This discovery ultimately led to the recognition that age …

Alzheimer's disease (AD) is the most common form of dementia, which affects more than 35
million people worldwide with increasing tendency. Satisfying therapies and prevention are …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the central
nervous system leading to the most common form of age-associated dementia. More than a …

It is currently estimated that over 35 million people worldwide have dementia, and with
demographic trends of an aging global population this figure is expected to triple by 2050 …

The hallmark pathologic lesions of Alzheimer's disease (AD) are extracellular senile
plaques, composed by Amiloid β (Aβ) peptide and intraneuronal neurofibrillary tangles …