Abstract Oral Squamous Cell Carcinoma (OSCC) is the sixth most common cancer
worldwide. Chemoresistance is a critical problem in OSCC leading to therapeutic failure and …

Despite the challenges posed by drug resistance and side effects, chemotherapy remains a
pivotal strategy in cancer treatment. A key issue in this context is macroautophagy …

Background Oral squamous cell carcinoma (OSCC) is one of the most common forms of oral
cancer and is known to have poor prognostic outcomes. Autophagy is known to be …

Oxaliplatin-based chemotherapy is used for treating gastric cancer. Autophagy has been
extensively implicated in cancer cells; however, its function is not fully understood. Our study …

The function of autophagy in cisplatin-treated cancer cells is not fully understood. Cisplatin
treatment induced degradation of ubiquitinated proteins by autophagy, which reduced …

Chemotherapy is one of the main methods of cancer treatment and is known to induce
autophagy in cancer cells. The main mechanism of chemotherapeutic agents is to promote …

Oxaliplatin is included in a number of effective combination regimens used as first and
subsequent lines of therapy for metastatic colorectal cancer. Accumulating evidence …

The majority of chemotherapy treatments for lung cancer use cisplatin; however, its use is
limited as it has several side-effects. Autophagy (or type II cell death) is an important …

Since the 1940s, chemotherapy has been the treatment of choice for metastatic disease.
Chemotherapeutic agents target proliferating cells, inducing cell death. For most of the …

Cisplatin-based chemotherapy frequently resulted in acquired resistance of cancer cells.
The underlying mechanism of such resistance is not fully understood especially the …