The enteroendocrine cell (EEC)-derived incretins play a pivotal role in regulating the
secretion of glucagon and insulins in mammals. Although glucagon-like and insulin-like …

Insulin/IGF-like signaling regulates the development, growth, fecundity, metabolic
homeostasis, stress resistance and lifespan in worms, flies and mammals. Eight insulin-like …

Animals must adapt their dietary choices to meet their nutritional needs. How these needs
are detected and translated into nutrient-specific appetites that drive food-choice behaviours …

Highlights•Fluorescent tagging enables detailed analysis of enteroendocrine cell
physiology.•Electrogenic nutrient uptake evokes electrical activity and hormone secretion.•G …

Neuropeptides regulate a wide range of animal behavior including food consumption,
circadian rhythms, and anxiety. Recently, Drosophila neuropeptide F, which is the homolog …

Developing organisms use fine-tuning mechanisms to adjust body growth to ever-changing
nutritional conditions. In Drosophila, the secretory activity of insulin-producing cells (IPCs) is …

Insulin, a highly conserved peptide hormone, links nutrient availability to metabolism and
growth in animals. In fed states insulin levels remain high and in animals that are food …

Regulatory peptides were immunolocalized in the midgut of the fruit fly Drosophila
melanogaster. Endocrine cells were found to produce six different peptides: allatostatins A …

The current view of the control of food intake involves a central feeding system in the
hypothalamus receiving input from peripheral systems. The presence of food in the gut …

Regulation of food intake by gastrointestinal hormones : Current Opinion in
Gastroenterology Regulation of food intake by gastrointestinal hormones : Current Opinion …