Vascular endothelial growth factor-A (VEGF-A) is a key mediator of angiogenesis, signalling
via the class IV tyrosine kinase receptor family of VEGF Receptors (VEGFRs). Although …

The VEGF-A isoforms play a crucial role in vascular development, and the VEGF signaling
pathway is a clinically validated therapeutic target for several pathological conditions …

Vascular endothelial growth factor A (VEGF-A) binding to the receptor tyrosine kinase
VEGFR2 triggers multiple signal transduction pathways, which regulate endothelial cell …

VEGF signaling often represents a critical rate-limiting step in physiological angiogenesis.
The VEGF family comprises seven secreted glycoproteins that are designated VEGF-A …

Vascular endothelial growth factor A (VEGF-A or VEGF) is a highly conserved secreted
signalling protein best known for its roles in vascular development and angiogenesis. Many …

Vascular endothelial growth factors (VEGFs) bind to membrane receptors on a wide variety
of cells to regulate diverse biological responses. The VEGF-A family member promotes …

Angiogenesis involves endothelial cell differentiation, proliferation, migration and cord
formation, which lead to tubulogenesis to form vessels. One group of growth factor receptors …

The formation of new blood vessels (angiogenesis) is critical for both embryonic
development and a variety of normal postnatal physiological processes. Various …

Vascular endothelial growth factor (VEGF) has proven to be the most critical angiogenic
factor identified to date; its discovery has transformed the field of angiogenesis research …

Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular
endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a …