In Silico Screening and Evolution of Promising Novel Anti-Virulents Against Salmonella ATPase
L Xu, N Shen - 2023 - chemrxiv.org
Our current treatments for bacterial infections are under threat by the growth of antibiotic
resistance in many different pathogens. Of these pathogens, Salmonella is a particularly …
resistance in many different pathogens. Of these pathogens, Salmonella is a particularly …
[PDF][PDF] Targeting the Invasion Protein A from the Type Three Secretion System of Salmonella Typhi: A Comprehensive Computational Drug Design Approach
NL SWATHI - 2023 - researchgate.net
Abstract Background: Salmonella enterica serovar Typhi is a significant human pathogen
causing enteric typhoid fever. Multidrug-resistant strains have emerged due to indiscriminate …
causing enteric typhoid fever. Multidrug-resistant strains have emerged due to indiscriminate …
[HTML][HTML] High-Throughput Chemical Screening for Inhibitors of Salmonella Pathogenicity Island 2
CN Tsai, BK Coombes - STAR protocols, 2020 - Elsevier
Anti-virulence therapies are under active investigation as antibiotic alternatives; however,
their identification from large-scale chemical libraries poses a unique challenge. The …
their identification from large-scale chemical libraries poses a unique challenge. The …
Discovery of a synthetic small molecule targeting the central regulator of Salmonella pathogenicity
The enteric pathogen Salmonella enterica serovar Typhimurium relies on the activity of
effector proteins to invade, replicate, and disseminate into host epithelial cells and other …
effector proteins to invade, replicate, and disseminate into host epithelial cells and other …
Deployment of in-silico analysis to reveal the antibacterial profiles of Allium sativum against Aeromonas hydrophila
MK Savita, V Dwivedi, P Srivastava - Journal of Biomolecular …, 2023 - Taylor & Francis
The key challenges in aquaculture are the emergence of antimicrobial resistance in fish
cultivation due to the frequent use of antibiotics. Over the past three decades, this led to a …
cultivation due to the frequent use of antibiotics. Over the past three decades, this led to a …
Computational evaluation of efflux pump homologues and lignans as potent inhibitors against multidrug-resistant Salmonella typhi
Typhoid fever, caused by Salmonella enterica serovar typhi, presents a substantial global
health threat, particularly in regions with limited healthcare infrastructure. The rise of …
health threat, particularly in regions with limited healthcare infrastructure. The rise of …
[PDF][PDF] Identification of a novel therapeutic target against XDR Salmonella Typhi H58 using genomics driven approach followed up by natural products virtual …
Typhoid fever is caused by a pathogenic, rod-shaped, flagellated, and Gram-negative
bacterium known as Salmonella Typhi. It features a polysaccharide capsule that acts as a …
bacterium known as Salmonella Typhi. It features a polysaccharide capsule that acts as a …
Paradigm Shift in Drug Re-purposing From Phenalenone to Phenaleno-Furanone to Combat Multi-Drug Resistant Salmonella enterica Serovar Typhi
S Mujawar, D Gatherer, C Lahiri - Frontiers in cellular and infection …, 2018 - frontiersin.org
Over recent years, typhoid fever has gained increasing attention with several cases
reporting treatment failure due to multidrug resistant (MDR) strains of Salmonella enterica …
reporting treatment failure due to multidrug resistant (MDR) strains of Salmonella enterica …
Dual transcriptome based reconstruction of Salmonella-human integrated metabolic network to screen potential drug targets
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a highly adaptive pathogenic
bacteria with a serious public health concern due to its increasing resistance to antibiotics …
bacteria with a serious public health concern due to its increasing resistance to antibiotics …
Identification of Potential Therapeutics to Conquer Drug Resistance in Salmonella typhimurium: Drug Repurposing Strategy
Background Salmonella typhimurium is the main cause of gastrointestinal illness in humans,
and treatment options are decreasing because drug-resistant strains have emerged …
and treatment options are decreasing because drug-resistant strains have emerged …