Machine perfusion has developed rapidly since its first use in solid organ transplantation.
Likewise, reconstructive surgery has kept pace, and ex vivo perfusion appears as a new …

Background Under ideal circumstances, creation of the anastomosis during free flap transfer
is a routine task and can be performed under short ischemia time. However, vessels may be …

In free flap surgery, a clinically established concept still has to be found for the reduction of
ischemia-related cell damage in the case of prolonged ischemia. Although promising results …

Background Extracorporeal perfusion is a promising new technique for prolonged
preservation of free flaps and extremities; however, uncertainties on perfusion settings and …

Background Machine perfusion is gaining interest as an efficient method of tissue
preservation of Vascularized Composite Allografts (VCA). The aim of this study was to …

Background Extracorporeal perfusion (ECP) might prolong the vital storage capabilities of
composite free flaps, potentially opening a wide range of clinical applications. Aim of the …

Background Extracorporeal perfusion is a technique that aims to safely prolong tissue
preservation by reducing ischemia-reperfusion injury. Free muscle flaps provide a sensitive …

Background: One of the major challenges in traumatic amputation is the need to keep
ischemia time brief (4 to 6 hours) to avoid ischemic damage and enable successful …

Background Attempts to improve limb preservation for transplantation using ex vivo
perfusion have yielded promising results. However, metabolic acidosis, aberrant perfusate …

Severe injuries of the face and limbs remain a major challenge in today's reconstructive
surgery. Vascularized composite allotransplantation (VCA) has emerged as a promising …