Major constraints in development of new product are poor aqueous solubility, stability and
low oral bioavailability, low permeability. As majority of drugs marketed worldwide are …

Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient
are the major constraints during the development of new product. Various approaches have …

Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient
are the major constraints during the development of new product. Various approaches have …

Poor dissolution rate, solubility, bioavailability, chemical stability and moisture uptake are
problems associated with most of the active pharmaceutical ingredients. Various …

Poor aqueous solubility and low oral bioavailability of an active pharmaceutical ingredient
are the major constraints during the development of new product. Various approaches have …

Cocrystal is a concept of the supramolecular chemistry which is gaining the extensive
interest of researchers from pharmaceutical and chemical sciences and of drug regulatory …

Crystal form can be crucial to the performance of a dosage form. This is especially true for
compounds that have intrinsic barriers to drug delivery, such as low aqueous solubility, slow …

Pharmaceutical co-crystals have conferred significant recognition in recent past as a new
solid form by virtue their capability to modulate physicochemical properties of Active …

Pharmaceutical active ingredients (APIs) can exist in a variety of distinct solid forms,
including polymorphs, solvates, hydrates, salts, co crystals and amorphous solids. Each form …

Background: Cocrystals of active pharmaceutical ingredient has been of interest in the field
of pharmaceutical research due to their potential for tailoring the physicochemical properties …