Potassium channels, glucose metabolism and glycosylation in cancer cells

A Wawrzkiewicz-Jałowiecka, A Lalik… - International Journal of …, 2023 - mdpi.com
Potassium channels emerge as one of the crucial groups of proteins that shape the biology
of cancer cells. Their involvement in processes like cell growth, migration, or electric …

Molecular research of glycolysis

YC Chang, CH Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
Glycolysis represents the process of breaking down monosaccharides, which involves the
energy metabolism, homeostasis, and the linkage of various physiological functions such as …

Glycolytic genes in cancer cells are more than glucose metabolic regulators

ZY Hu, L Xiao, AM Bode, Z Dong, Y Cao - Journal of Molecular Medicine, 2014 - Springer
Nearly a hundred years of scientific research has revealed a notable preference of cancer
cells to utilize aerobic glycolysis rather than mitochondrial oxidative phosphorylation for …

How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions?

H Lincet, P Icard - Oncogene, 2015 - nature.com
Cancer cells enhance their glycolysis, producing lactate, even in the presence of oxygen.
Glycolysis is a series of ten metabolic reactions catalysed by enzymes whose expression is …

Crucial players in glycolysis: cancer progress

Z Abbaszadeh, S Çeşmeli, ÇB Avcı - Gene, 2020 - Elsevier
Cancer is the second most important cause of death and new therapy modalities continue to
be developed and evolved. Cancer cells' metabolism is far different from the normal, healthy …

Tumor glycolysis, an essential sweet tooth of tumor cells

S Paul, S Ghosh, S Kumar - Seminars in cancer biology, 2022 - Elsevier
Cancer cells undergo metabolic alterations to meet the immense demand for energy,
building blocks, and redox potential. Tumors show glucose-avid and lactate-secreting …

The regulatory roles and clinical significance of glycolysis in tumor

Q Qiao, S Hu, X Wang - Cancer Communications, 2024 - Wiley Online Library
Metabolic reprogramming has been demonstrated to have a significant impact on the
biological behaviors of tumor cells, among which glycolysis is an important form. Recent …

Glycolytic pathway as a target for tumor inhibition

W Lu, P Huang - The Tumor Microenvironment, 2010 - Springer
It has been known for decades that cancer cells exhibit elevated aerobic glycolysis, a
phenomenon first observed by Otto Warburg. The imaging technique 18 fluoro …

Functional importance of glucose transporters and chromatin epigenetic factors in Glioblastoma Multiforme (GBM): possible therapeutics

S Chamarthy, JR Mekala - Metabolic Brain Disease, 2023 - Springer
Glioblastoma Multiforme (GBM) is an aggressive brain cancer affecting glial cells and is
chemo-and radio-resistant. Glucose is considered the most vital energy source for cancer …

New strategies for targeting glucose metabolism–mediated acidosis for colorectal cancer therapy

G Wang, JJ Wang, PH Yin, K Xu… - Journal of cellular …, 2019 - Wiley Online Library
Colorectal cancer (CRC) is a heterogeneous group of diseases that are the result of
abnormal glucose metabolism alterations with high lactate production by pyruvate to lactate …