Oxidative stress has been implicated in the pathogenesis of osteoarthritis and has become
an important therapeutic target. Investigations of various antioxidant supplements, reactive …

Reactive oxygen species (ROS) play distinct but important roles in physiological and
pathophysiological processes. Recent studies on osteoarthritis (OA) have suggested that …

Anti-oxidative agents hold great potential in osteoarthritis (OA) therapy. However, most
radical scavengers have poor biocompatibility and potential cytotoxicity, which limit their …

Osteoarthritis (OA) is a progressive degenerative joint disease whose molecular mechanism
has not been revealed clearly, and there is still no effective approach to cure OA completely …

The emerging therapeutic strategies for osteoarthritis (OA) are shifting toward
comprehensive approaches that target periarticular tissues, involving both cartilage and …

Oxidative stress and the reactive oxygen species (ROS) have important roles in
osteoarthritis (OA) development and progression. Scavenging ROS by exogenous …

Targeting cartilage is a promising strategy for the treatment of osteoarthritis, and various
delivery vehicles were developed to assist the therapeutic agents into cartilage. However …

Background Osteoarthritis (OA) is a common joint disorder worldwide which causes great
health and economic burden. However, there remains an unmet goal to develop an effective …

Utilization of joint-resident mesenchymal stem cells (MSC) to repair articular cartilage is a
promising strategy in osteoarthritis (OA) therapy but remains a considerable research …

Since the progression of osteoarthritis (OA) is closely associated with synovitis and cartilage
destruction, the inhibition of inflammatory responses in synovial macrophages and reactive …