Probiotics (Lactobacillus acidophilus and Lactobacillus rhamnosus GG) in Conjunction with Celecoxib (selective COX-2 inhibitor) Modulated DMH-Induced Early …

L Kaeid Sharaf, G Shukla - Nutrition and cancer, 2018 - Taylor & Francis
Epidemiological and experimental observations have shown that nonsteroidal anti-
inflammatory drugs especially selective cyclooxygenase-2 (COX-2) inhibitors and probiotics …

Prophylactic intervention of probiotics (L.acidophilus, L.rhamnosus GG) and celecoxib modulate Bax-mediated apoptosis in 1,2-dimethylhydrazine-induced …

LK Sharaf, M Sharma, D Chandel, G Shukla - BMC cancer, 2018 - Springer
Background Colorectal cancer has been found to be attenuated either with prophylactic
manipulation of gut microbiome with probiotics or celecoxib, a non-steroidal anti …

Cyclooxygenase as a target in chemoprevention by probiotics during 1, 2-dimethylhydrazine induced colon carcinogenesis in rats

S Walia, R Kamal, SS Kanwar, DK Dhawan - Nutrition and cancer, 2015 - Taylor & Francis
The present study was undertaken to assess the effects of potential probiotics in regulating
the activity of cyclooxygenase-2 (COX-2) along with other morphological and histological …

Effects of probiotic supplementation on chronic inflammatory process modulation in colorectal carcinogenesis

SK Reis, EAR Socca, BR de Souza, SC Genaro… - Tissue and Cell, 2024 - Elsevier
The current study investigated the potential effects of probiotic supplementation on
colorectal carcinogenesis chemically induced with 1, 2-dimethylhydrazine (DMH) and …

Chemoprevention by probiotics during 1, 2-dimethylhydrazine-induced colon carcinogenesis in rats

S Walia, R Kamal, DK Dhawan, SS Kanwar - Digestive diseases and …, 2018 - Springer
Background Probiotics are believed to have properties that lower the risk of colon cancer.
However, the mechanisms by which they exert their beneficial effects are relatively …

Probiotics Lactobacillus rhamnosus GG, Lactobacillus acidophilus Suppresses DMH-Induced Procarcinogenic Fecal Enzymes and Preneoplastic Aberrant Crypt …

A Verma, G Shukla - Nutrition and cancer, 2013 - Taylor & Francis
Diet makes an important contribution to colorectal cancer (CRC) risk implying risks for CRC
are potentially reducible. Therefore, the probiotics have been suggested as the prophylactic …

Synbiotic (Lactobacillus rhamnosus+ Lactobacillus acidophilus+ inulin) attenuates oxidative stress and colonic damage in 1, 2 dimethylhydrazine dihydrochloride …

A Verma, G Shukla - European Journal of Cancer Prevention, 2014 - journals.lww.com
The inexorable increase in the incidence of colorectal cancer has led to growing interest in
its prevention by natural interventions. Thus, the present study was designed with the aim of …

Probiotics prevent the development of 1, 2-dimethylhydrazine (DMH)-induced colonic tumorigenesis through suppressed colonic mucosa cellular proliferation and …

NP Foo, H Ou Yang, HH Chiu, HY Chan… - Journal of agricultural …, 2011 - ACS Publications
Probiotics modulate immunity and inhibit colon carcinogenesis in experimental models, but
these effects largely depend on the bacterial strain, and the precise mechanisms are not …

Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model

Y Gamallat, A Meyiah, ED Kuugbee, AM Hago… - Biomedicine & …, 2016 - Elsevier
Abstract Background/Aim Probiotics have been suggested as prophylactic measure in colon
carcinogenesis. This study aimed at determining the potential prophylactic activity of …

Prebiotic treatment reduced preneoplastic lesions through the downregulation of toll like receptor 4 in a chemo-induced carcinogenic model

F Masanobu, K Yutaka, K Mitsuyama… - Journal of Clinical …, 2011 - jstage.jst.go.jp
抄録 Germinated barley foodstuff contains prebiotics which are reported to have anti-
cancerous effects in colorectal cancer model, but the detailed mechanism remains unclear …