Uric acid (UA) is the end product of purine metabolism, and its concentration in blood can
increase in humans, great apes, and dalmatian dogs as a consequence of a genetic …

The definition of hyperuricemia (HU) varies widely in different studies, which makes the
epidemiological reports somewhat inconsistent. HU remains the culprit of the pathogenesis …

Hyperuricemia is commonly associated with traditional risk factors such as dysglicemia,
dyslipidemia, central obesity and abnormal blood pressure, ie the metabolic syndrome …

Background: Hyperuricemia and gout have become public health concerns; many important
guidelines have recommended xanthine oxidase inhibitors (XOIs) as the first-line urate …

Introduction Hyperuricemia is an overlooked cardiovascular and renal risk factor.
Epidemiological and genetic studies have shown an independent role of uric acid in the risk …

Objective: This study aimed to evaluate the potential association between uric acid (UA)
lowering and cardiovascular risk reduction among UA-lowering therapies in adults …

Background Hyperuricemia may be associated with an increased risk of coronary heart
disease (CHD) mortality; however, the results from prospective studies are conflicting. The …

In recent years, there has been an increase in the prevalence of hyperuricemia, and the
latter has attracted attention as an adult lifestyle-associated disease, together with …

Background Hyperuricemia (HUA) is associated with hypertension and increased
cardiovascular risk. Current data regarding the prevalence of HUA in Chinese hypertensive …

Background Hyperuricemia is associated with cardiovascular mortality, but the association
of the age at hyperuricemia onset with cardiovascular disease (CVD) and mortality is still …