Fungal aflatoxins reduce respiratory mucosal ciliary function
Aflatoxins are mycotoxins secreted by Aspergillus flavus, which can colonize the respiratory
tract and cause fungal rhinosinusitis or bronchopulmonary aspergillosis. A. flavus is the …
tract and cause fungal rhinosinusitis or bronchopulmonary aspergillosis. A. flavus is the …
Verruculogen associated with Aspergillus fumigatus hyphae and conidia modifies the electrophysiological properties of human nasal epithelial cells
Abstract Background The role of Aspergillus fumigatus mycotoxins in the colonization of the
respiratory tract by conidia has not been studied extensively, even though patients at risk …
respiratory tract by conidia has not been studied extensively, even though patients at risk …
Elimination of Aspergillus fumigatus conidia from the airways of mice with allergic airway inflammation
MA Shevchenko, EL Bolkhovitina, EA Servuli… - Respiratory …, 2013 - Springer
Background Aspergillus fumigatus conidia can exacerbate asthma symptoms. Phagocytosis
of conidia is a principal component of the host antifungal defense. We investigated whether …
of conidia is a principal component of the host antifungal defense. We investigated whether …
The Impact of Aspergillus fumigatus Viability and Sensitization to Its Allergens on the Murine Allergic Asthma Phenotype
S Pandey, SA Hoselton… - BioMed Research …, 2013 - Wiley Online Library
Aspergillus fumigatus is a ubiquitously present respiratory pathogen. The outcome of a
pulmonary disease may vary significantly with fungal viability and host immune status. Our …
pulmonary disease may vary significantly with fungal viability and host immune status. Our …
Aspergillus fumigatus cell wall promotes apical airway epithelial recruitment of human neutrophils
MB Feldman, RA Dutko, MA Wood, RA Ward… - Infection and …, 2020 - Am Soc Microbiol
Aspergillus fumigatus is a ubiquitous fungal pathogen capable of causing multiple
pulmonary diseases, including invasive aspergillosis, chronic necrotizing aspergillosis …
pulmonary diseases, including invasive aspergillosis, chronic necrotizing aspergillosis …
Aspergillus fumigatus Inhibits Pseudomonas aeruginosa in Co-culture: Implications of a Mutually Antagonistic Relationship on Virulence and Inflammation in the CF …
Many cystic fibrosis (CF) airway infections are considered to be polymicrobial and microbe–
microbe interactions may play an important role in disease pathology. Pseudomonas …
microbe interactions may play an important role in disease pathology. Pseudomonas …
Characterization of Lung Inflammatory Response to Aspergillus fumigatus Spores
A Bouyssi, T Déméautis, A Trecourt, M Delles… - Journal of Fungi, 2023 - mdpi.com
The airway exposure to Aspergillus fumigatus spores (AFsp) is associated with an
inflammatory response, potentially leading to allergic and/or chronic pulmonary …
inflammatory response, potentially leading to allergic and/or chronic pulmonary …
Aspergillus fumigatus viability drives allergic responses to inhaled conidia
AP Nayak, TL Croston, AR Lemons… - Annals of Allergy …, 2018 - Elsevier
Background Aspergillus fumigatus–induced allergic airway disease has been shown to
involve conidial germination in vivo, but the immunological mechanisms remain …
involve conidial germination in vivo, but the immunological mechanisms remain …
Exposure to Aspergillus fumigatus spores induces chemokine expression in mouse macrophages
L Pylkkänen, H Gullstén, ML Majuri, U Andersson… - Toxicology, 2004 - Elsevier
Inhalation of fungal spores may cause inflammation and respiratory diseases, such as
bronchitis, allergic alveolitis, and asthma. Alveolar macrophages provide the first line of …
bronchitis, allergic alveolitis, and asthma. Alveolar macrophages provide the first line of …
Aspergillus‐Associated Airway Disease, Inflammation, and the Innate Immune Response
SH Chotirmall, M Al-Alawi, B Mirkovic… - BioMed research …, 2013 - Wiley Online Library
Aspergillus moulds exist ubiquitously as spores that are inhaled in large numbers daily.
Whilst most are removed by anatomical barriers, disease may occur in certain …
Whilst most are removed by anatomical barriers, disease may occur in certain …