Two distinct nuclear factor κB (NFκB) signaling pathways have been described; the
canonical pathway that mediates inflammatory responses, and the non-canonical pathway …

The nuclear factor kappa B (NFκB) family of transcription factors is a key regulator of immune
development, immune responses, inflammation, and cancer. The NFκB signaling system …

Mathematical modeling has proved to be a critically important approach in the study of many
complex networks and dynamic systems in physics, engineering, chemistry, and biology …

Abstract The Nuclear Factor-kappa B (NF-κB) family of transcription factors regulates the
expression of a wide range of genes critical for immune and inflammatory responses, cell …

A major regulator of lymphocyte survival and activation is the transcription factor nuclear
factor-κB (NF-κB). Controlled activation of NF-κB is essential for the immune and …

The IKKβ and NEMO/IKKγ subunits of the NF-κB-activating signalsome complex are known
to be essential for activating NF-κB by inflammatory and other stress-like stimuli. However …

Nuclear factor (NF)-κB proteins play crucial roles in immune responses and cellular survival.
Activation of NF-κB is mediated by the IκB kinase (IKK) complex, which is composed of two …

The NF-κB family of transcription factors plays a crucial role in the immune, inflammatory and
apoptotic responses. These proteins are normally found in the cytoplasm, retained by …

The NF-κB-inducing kinase (NIK) induces proteolytic processing of NF-κB2/p100 and,
hence, the generation of NF-κB dimers such as p52: RelB but was suggested not to signal …

Abstract The NF-κB (Nuclear Factor kappa B) transcription factor plays crucial roles in the
regulation of numerous biological processes including development of the immune system …