The role of Epstein-Barr virus in modulating key tumor suppressor genes in associated malignancies: epigenetics, transcriptional, and post-translational modifications

AO Fierti, MB Yakass, EA Okertchiri, SM Adadey… - Biomolecules, 2022 - mdpi.com
Epstein-Barr virus (EBV) is ubiquitous and carried by approximately 90% of the world's adult
population. Several mechanisms and pathways have been proposed as to how EBV …

Epstein–Barr virus and cancer

PJ Farrell - Annual Review of Pathology: Mechanisms of …, 2019 - annualreviews.org
Epstein–Barr virus (EBV) contributes to about 1.5% of all cases of human cancer worldwide,
and viral genes are expressed in the malignant cells. EBV also very efficiently causes the …

The impact of Epstein-Barr virus infection on epigenetic regulation of host cell gene expression in epithelial and lymphocytic malignancies

MML Leong, ML Lung - Frontiers in Oncology, 2021 - frontiersin.org
Epstein-Barr virus (EBV) infection is associated with a variety of malignancies including
Burkitt's lymphoma (BL), Hodgkin's disease, T cell lymphoma, nasopharyngeal carcinoma …

[HTML][HTML] Themed issue: the biology and pathology of the Epstein-Barr virus

PG Murray, LS Young - Molecular Pathology, 2000 - ncbi.nlm.nih.gov
Based on their genomic organisation, tissue tropism, and other biological characteristics,
herpesviruses are classified into three categories: α, β, and γ. Of these, the γ-herpesviruses …

Epstein-Barr virus: Biology and clinical disease

B Damania, SC Kenney, N Raab-Traub - Cell, 2022 - cell.com
Epstein-Barr virus (EBV) is a ubiquitous, oncogenic virus that is associated with a number of
different human malignancies as well as autoimmune disorders. The expression of EBV viral …

Epstein–Barr virus-associated malignancies: Roles of viral oncoproteins in carcinogenesis

A El-Sharkawy, L Al Zaidan, A Malki - Frontiers in oncology, 2018 - frontiersin.org
The Epstein–Barr virus (EBV) is the first herpesvirus identified to be associated with human
cancers known to infect the majority of the world population. EBV-associated malignancies …

Epstein–barr virus history and pathogenesis

H Yu, ES Robertson - Viruses, 2023 - mdpi.com
Epstein–Barr virus (EBV) is the first identified human oncogenic virus that can establish
asymptomatic life-long persistence. It is associated with a large spectrum of diseases …

[HTML][HTML] The expression and function of Epstein-Barr virus encoded latent genes

LS Young, CW Dawson, AG Eliopoulos - Molecular Pathology, 2000 - ncbi.nlm.nih.gov
Abstract The association of Epstein-Barr virus (EBV) with various malignancies is well
established but the pattern of EBV latent gene expression in these different tumours is …

[PDF][PDF] Epstein-Barr virus (EBV) and its associated human cancers–genetics, epigenetics, pathobiology and novel therapeutics

Q Tao, LS Young, CB Woodman, PG Murray - Front Biosci, 2006 - researchgate.net
Introduction 3. Genetics of EBV 3.1. Genome structure 3.2. EBV strain variations 4. EBV
primary infection and persistence 4.1. In vitro models of EBV infection 4.2. EBV persistence …

Epstein–Barr virus: more than 50 years old and still providing surprises

LS Young, LF Yap, PG Murray - Nature reviews cancer, 2016 - nature.com
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …