The molecular landscape of head and neck cancer

CR Leemans, PJF Snijders, RH Brakenhoff - Nature Reviews Cancer, 2018 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …

[HTML][HTML] Molecular landscape of head and neck cancer and implications for therapy

CS Farah - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinomas (HNSCC) arising from the oral cavity, pharynx,
and larynx constitute the 6 th most common human cancer. Human papillomavirus (HPV) …

[HTML][HTML] Clinical update on head and neck cancer: molecular biology and ongoing challenges

E Alsahafi, K Begg, I Amelio, N Raulf, P Lucarelli… - Cell death & …, 2019 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) are an aggressive, genetically
complex and difficult to treat group of cancers. In lieu of truly effective targeted therapies …

[HTML][HTML] Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

Head and neck squamous cell carcinoma: Genomics and emerging biomarkers for immunomodulatory cancer treatments

B Solomon, RJ Young, D Rischin - Seminars in cancer biology, 2018 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) comprises a heterogeneous group of
tumors that arise from the squamous epithelium of the oral cavity, oropharynx, larynx and …

[HTML][HTML] Genomic insights into head and neck cancer

TN Beck, EA Golemis - Cancers of the head & neck, 2016 - Springer
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide and is frequently impervious to curative treatment efforts. Similar to other cancers …

[HTML][HTML] Heterogeneity of the head and neck squamous cell carcinoma immune landscape and its impact on immunotherapy

M Canning, G Guo, M Yu, C Myint… - Frontiers in cell and …, 2019 - frontiersin.org
Head and neck squamous cell carcinomas (HNSCCs) are highly aggressive, multi-factorial
tumors in the upper aerodigestive tract affecting more than half a million patients worldwide …

Head and neck cancer: Current challenges and future perspectives

GR Bhat, RG Hyole, J Li - Advances in Cancer Research, 2021 - Elsevier
Head and neck cancers are a heterogeneous, aggressive and genetically complex
collection of malignancies of the oral cavity, nasopharynx, oropharynx, hypopharynx, larynx …

[HTML][HTML] Current trends and future prospects of molecular targeted therapy in head and neck squamous cell carcinoma

N Kitamura, S Sento, Y Yoshizawa, E Sasabe… - International journal of …, 2020 - mdpi.com
In recent years, advances in drug therapy for head and neck squamous cell carcinoma
(HNSCC) have progressed rapidly. In addition to cytotoxic anti-cancer agents such as …

Therapeutic insights from genomic studies of head and neck squamous cell carcinomas

PS Hammerman, DN Hayes, JR Grandis - Cancer discovery, 2015 - AACR
Large and comprehensive genomic surveys of head and neck squamous cell carcinomas
(HNSCC) are now greatly increasing our understanding of the diversity of this disease and …