As a research hotspot, the development of magnetic resonance imaging (MRI) contrast
agents has attracted great attention over the past decades for improving the accuracy of …

Nanotechnology has given scientists new tools for the development of advanced materials
for the detection and diagnosis of various types of diseases. In particular, ultrasmall …

Ultrasmall superparamagnetic iron oxide (USPIO) particles are maghemite or magnetite
nanoparticles currently used as contrast agent in magnetic resonance imaging. The coatings …

Superparamagnetic iron oxide nanoparticles have received great attention due to their
applications as contrast agents for magnetic resonance imaging (MRI). This feature article …

For the application of superparamagnetic iron oxide nanoparticles in biomedical fields for
target-specific purposes, they should be ultra small in diameter. We developed a simple one …

A facile method to synthesize ultrasmall-sized supermagnetic iron oxide nanoparticles with
good monodispersity and high relaxivity is desired for magnetic resonance imaging (MRI) …

Highlights•Surface engineering of SPION determines their in vivo performance.•Targeting
mechanisms of SPION imaging are summarized.•Clinical trial information related to SPION …

Despite significant advances in cancer therapy over the years, its complex pathological
process still represents a major health challenge when seeking effective treatment and …

Aims The purpose of this clinical trial was to investigate whether cardiovascular magnetic
resonance imaging (CMR) using ferumoxytol (Feraheme™, FH), an ultrasmall …

This paper aims to update the clinical researches using superparamagnetic iron oxide
(SPIO) nanoparticles as magnetic resonance imaging (MRI) contrast agent published during …