Formation of an imine—from an amine and an aldehyde—is a reversible reaction which
operates under thermodynamic control such that the formation of kinetically competitive …

The imine bond–formed by the reversible condensation of an amine and an aldehyde–and
its applications as a dynamic covalent bond in the template-directed synthesis of molecular …

Mechanically interlocked molecular compounds can be synthesized in high yields by using
template-directed assistance to covalent synthesis. Catenanes and rotaxanes are two …

The template‐directed construction of crown‐ether‐like macrocycles around secondary
dialkylammonium ions (R2NH2+) has been utilized for the expedient (one‐pot) and high …

The active template approach to interlocked molecules takes advantage of the ability of
metal ions to both organize precursor fragments for mechanical bond formation and to …

The emergence of the mechanical bond during the past 25 years is giving chemistry a fillip
in more ways than one. While its arrival on the scene is already impacting materials science …

The quest to construct mechanically interlocked polymers, which present precise
monodisperse primary structures that are produced both consistently and with high …

Mechanically interlocked molecules (MIMs), such as rotaxanes, catenanes, and molecular
knots, have attracted significant interest because of their unique properties originating from …

More than a quarter of a century after the first metal template synthesis of a [2] catenane in
Strasbourg, there now exists a plethora of strategies available for the construction of …

Active metal template synthesis is a powerful new strategy for the construction of rotaxanes,
catenanes and other mechanically interlocked molecular structures. The key feature is that …