Introduction Neuronal cell death is an important factor in the pathogenesis of acute high-
altitude cerebral hypoxia; however, the underlying molecular mechanism remains unclear …

This study was conducted to establish a stable hypobaric hypoxia brain injury model. SD
rats were randomly separated into control and model groups, and placed outside or inside of …

Objective The aim of this study was to investigate the effect of time course on neurological
impairment after acute hypobaric hypoxia exposure in mice and clarify the mechanism of …

Hypobaric hypoxia can cause severe brain damage and mitochondrial dysfunction, and is
involved in hypoxic brain injury. However, little is currently known about the mechanisms …

Hypobaric hypoxia (HH), a predisposing environmental condition at high altitude (HA),
encountered by many mountaineers, jeopardizes their normal physiology like motor …

Acute hypobaric hypoxic brain damage is a potentially fatal high-altitude sickness.
Autophagy plays a critical role in ischemic brain injury, but its role in hypobaric hypoxia (HH) …

Objective To determine changes in protein expression related to brain aging and imaging
features in mice after chronic hypoxia exposure at high altitude. Method A total of 24 healthy …

Obstructive sleep apnea (OSA) is a very common breathing and sleep disorder
characterized by intermittent hypoxia (IH), which is often associated with behavioral and …

The earth land area is heterogeneous in terms of elevation; about 45% of its land area
belongs to higher elevation with altitude above 500 meters compared to sea level. In most …

Ascend to high altitude results in a drastic change in the environmental conditions an
individual is exposed to. As the altitude increases there is a decrease in partial pressure of …