Parkinson's disease: potential actions of lithium by targeting the WNT/β-catenin pathway, oxidative stress, inflammation and glutamatergic pathway
A Vallée, JN Vallée, Y Lecarpentier - Cells, 2021 - mdpi.com
Parkinson's disease (PD) is one of the major neurodegenerative diseases (ND) which
presents a progressive neurodegeneration characterized by loss of dopamine in the …
presents a progressive neurodegeneration characterized by loss of dopamine in the …
Potential application of lithium in Parkinson's and other neurodegenerative diseases
CA Lazzara, YH Kim - Frontiers in neuroscience, 2015 - frontiersin.org
Lithium, the long-standing hallmark treatment for bipolar disorder, has recently been
identified as a potential neuroprotective agent in neurodegeneration. Here we focus on …
identified as a potential neuroprotective agent in neurodegeneration. Here we focus on …
Wnt and lithium: a common destiny in the therapy of nervous system pathologies?
D Meffre, J Grenier, S Bernard, F Courtin… - Cellular and Molecular …, 2014 - Springer
Wnt signaling is required for neurogenesis, the fate of neural progenitors, the formation of
neuronal circuits during development, neuron positioning and polarization, axon and …
neuronal circuits during development, neuron positioning and polarization, axon and …
Is lithium neuroprotective? An updated mechanistic illustrated review
F Ghanaatfar, A Ghanaatfar, P Isapour… - Fundamental & …, 2023 - Wiley Online Library
Neurodegeneration is a pathological process characterized by progressive neuronal
impairment, dysfunction, and loss due to mitochondrial dysfunction, oxidative stress …
impairment, dysfunction, and loss due to mitochondrial dysfunction, oxidative stress …
Neuroprotective effects of lithium: implications for the treatment of Alzheimer's disease and related neurodegenerative disorders
OV Forlenza, VJR De-Paula… - ACS chemical …, 2014 - ACS Publications
Lithium is a well-established therapeutic option for the acute and long-term management of
bipolar disorder and major depression. More recently, based on findings from translational …
bipolar disorder and major depression. More recently, based on findings from translational …
[HTML][HTML] Potential role of cannabidiol in Parkinson's disease by targeting the WNT/β-catenin pathway, oxidative stress and inflammation
A Vallée, JN Vallée, Y Lecarpentier - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a major neurodegenerative disease (ND), presenting a
progressive degeneration of the nervous system characterized by a loss of dopamine in the …
progressive degeneration of the nervous system characterized by a loss of dopamine in the …
An oldie but goodie: lithium in the treatment of bipolar disorder through neuroprotective and neurotrophic mechanisms
E Won, YK Kim - International journal of molecular sciences, 2017 - mdpi.com
Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more
years, and recent studies with more reliable designs and updated guidelines have …
years, and recent studies with more reliable designs and updated guidelines have …
Lithium and Disease Modification: A Systematic Review and Meta-analysis in Alzheimer's and Parkinson's Disease.
MP Singulani, AFF Ferreira, PS Figueroa… - Ageing Research …, 2024 - Elsevier
The role of lithium as a possible therapeutic strategy for neurodegenerative diseases has
generated scientific interest. We systematically reviewed and meta-analyzed pre-clinical and …
generated scientific interest. We systematically reviewed and meta-analyzed pre-clinical and …
Molecular mechanisms of lithium action: switching the light on multiple targets for dementia using animal models
Lithium has long been used for the treatment of psychiatric disorders, due to its robust
beneficial effect as a mood stabilizing drug. Lithium's effectiveness for improving …
beneficial effect as a mood stabilizing drug. Lithium's effectiveness for improving …
Potential mechanisms involved in the prevention of neurodegenerative diseases by lithium
A Camins, E Verdaguer, F Junyent… - CNS neuroscience & …, 2009 - Wiley Online Library
Lithium is a monovalent cation that was introduced in 1949 by John Cade for the treatment
of bipolar disorder. Clinical reports and subsequent studies confirmed this application and …
of bipolar disorder. Clinical reports and subsequent studies confirmed this application and …