White adipose tissue, once regarded as morphologically and functionally bland, is now
recognized to be dynamic, plastic and heterogenous, and is involved in a wide array of …

Our understanding of adipose tissue biology has progressed rapidly since the turn of the
century. White adipose tissue has emerged as a key determinant of healthy metabolism and …

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White adipose tissue displays high plasticity. We developed a system for the inducible,
permanent labeling of mature adipocytes that we called the AdipoChaser mouse. We …

White adipose tissue (WAT) is an essential regulator of energy storage and systemic
metabolic homeostasis. Regulatory networks consisting of immune and structural cells are …

Adipose tissue not only stores energy, but also controls metabolism through secretion of
hormones, cytokines, proteins, and microRNAs that affect the function of cells and tissues …

Adipose tissue is usually classified on the basis of its function as white, brown or beige
(brite). It is an important regulator of systemic metabolism, as shown by the fact that …

The complex relationship between metabolic disease risk and body fat distribution in
humans involves cellular characteristics that are specific to body fat compartments. Here we …

Adipocytes have been studied with increasing intensity as a result of the emergence of
obesity as a serious public health problem and the realization that adipose tissue serves as …

Obesity is increasing in an epidemic manner in most countries and constitutes a public
health problem by enhancing the risk for cardiovascular disease and metabolic disorders …