Mitogen-activated protein kinase (MAPK) cascades are key signalling pathways that
regulate a wide variety of cellular processes, including proliferation, differentiation …

The extracellular‐signal‐regulated kinase (ERK) mitogen‐activated protein (MAP) kinase
signaling pathway plays an important role in various cellular responses, including cell …

Mitogen-activated protein kinase (MAPK) cascades are key signaling pathways involved in
the regulation of normal cell proliferation, survival and differentiation. Aberrant regulation of …

The extracellular-regulated kinases ERK1 and ERK2 are evolutionarily conserved,
ubiquitous serine–threonine kinases that are involved in regulating cellular signaling in both …

ERK1 and ERK2 (ERKs), two extracellular regulated kinases (ERK1/2), are evolutionary-
conserved and ubiquitous serine-threonine kinases involved in regulating cell signalling in …

Abstract The RAS–RAF–MEK–ERK pathway is the most well-studied of the MAPK cascades
and is critical for cell proliferation, differentiation, and survival. Abnormalities in regulation …

Background The mitogen-activated protein (MAP) kinases p44 ERK1 and p42 ERK2 are
crucial components of the regulatory machinery underlying normal and malignant cell …

ERK1 and ERK2 are key protein kinases that contribute to the Ras-Raf-MEK-ERK MAP
kinase signalling module. This pathway participates in the control of numerous processes …

The RAF–MEK–ERK mitogen-activated protein kinase (MAPK) cascade is aberrantly
activated in a diverse set of human cancers and the RASopathy group of genetic …

The MAP kinases are ubiquitous enzymes that are activated in a complex fashion and
inactivated by multiple phosphatases including a dedicated dual specificity enzyme. These …