Accumulating evidence highlights the key importance of innate immunity in heart
hypertrophy and failure. Though stimulator of interferon genes (STING) is an integral innate …

Pathological cardiac hypertrophy is characterized by myocyte enlargement and cardiac
dysfunction. However, the pathogenesis for this disease is still poorly understood. Stimulator …

Background Heart failure, which is characterized by cardiac remodelling, is one of the most
common chronic diseases in the aged. Stimulator of interferon genes (STING) acts as an …

Stimulator of interferon genes (STING) has recently been found to play a crucial role in
cardiac sterile inflammation and dysfunction. The role of stimulator of interferon genes …

Mountainous evidence suggests that inflammation, cardiomyocyte apoptosis and pyroptosis
are involved in the development of sepsis and sepsis-induced cardiomyopathy (SIC) …

Aims Cardiac fibrosis is central to heart failure (HF), especially HF with preserved ejection
fraction (HFpEF), often caused by hypertension. Despite fibrosis causing diastolic …

Obesity has been identified as an independent risk factor for cardiovascular disease. Recent
reports have highlighted the significance of stimulator of interferon genes (STING)-NOD-like …

Aims This work sought to investigate the mechanism underlying the STING signaling
pathway during myocardial infarction (MI), and explore the involvement and the role of …

Macrophages play an essential role in the pathogenesis of autoimmune myocarditis, but the
molecular mechanism remains largely unknown. Here, the role of Stimulator of interferon …

Background: Although the past decade has witnessed substantial scientific progress with the
advent of cardioprotective pharmacological agents, most have failed to protect against …