Intestinal fibrosis is considered an inevitable complication of Crohn's disease (CD) that
results in symptoms of obstruction and stricture formation. Endoscopic or surgical treatment …

Crohn's disease (CD) is a chronic remitting and relapsing disease. Fibrostenosing
complications such as intestinal strictures, stenosis and ultimately obstruction are some of its …

Background The current therapies for Crohn's disease (CD) are mainly focused on blockade
of inflammation. Fibrosis remains one of the major complications of CD often leading to …

In Crohn's disease, one of the two major forms of inflammatory bowel diseases in human
beings, persistent and chronic inflammation promotes fibrotic processes thereby facilitating …

Crohn's disease (CD) is a chronic inflammatory disease, which could affect any part of the
gastrointestinal tract. A severe complication of CD is fibrosis-associated strictures, which can …

Introduction: Fibrostenosis is a hallmark of Crohn's disease (CD), remains a challenge in
today's clinical management of inflammatory bowel disease patients and represents a key …

Intestinal fibrosis is a common feature of Crohn's disease and may appear as a stricture,
stenosis, or intestinal obstruction. Fibrostenosing Crohn's disease leads to a significantly …

The concepts on the pathophysiology of intestinal fibrosis in Crohn's disease (CD) have
changed in recent years. Some years ago fibrosis was regarded to be a consequence of …

The use of biologic agents including anti-tumor necrosis factor monoclonal antibodies
followed by anti-integrins and anti-interleukins has drastically changed the treatment …

METHODS The electronic literature (January 1966 to May 2006) on CD-associated fibrosis
was reviewed. Further references were obtained by cross-referencing from key articles …