In neurological diseases, the actions of microglia, the resident myeloid cells of the CNS
parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive …

Monocytes are a heterogeneous population of bone marrow-derived cells that are recruited
to sites of infection and inflammation in many models of human diseases, including those of …

As immune sentinels of the central nervous system (CNS), microglia not only respond
rapidly to pathological conditions but also contribute to homeostasis in the healthy brain. In …

The immune system of the central nervous system (CNS) consists primarily of innate
immune cells. These are highly specialized macrophages found either in the parenchyma …

Specialized populations of tissue-resident myeloid cells inhabit every organ of the body.
While many of these populations appear similar morphologically and phenotypically, they …

Inflammation is a hallmark of different central nervous system (CNS) pathologies. It has been
linked to neurodegenerative disorders as well as primary and metastatic brain tumors …

Inflammation is a series of processes designed for eventual clearance of pathogens and
repair of damaged tissue. In the context of autoimmune recognition, inflammatory processes …

Microglia are resident immune cells that play multiple roles in central nervous system (CNS)
development and disease. Although the classical concept of microglia/macrophage …

Viral encephalitis is a devastating disease with high mortality, and survivors often suffer from
severe neurological complications. Microglia are innate immune cells of the central nervous …

Neuroinflammation is a hallmark of many neurodegenerative diseases (NDs) and plays a
fundamental role in mediating the onset and progression of disease. Microglia, which …