Objectives To determine the effects of astragaloside IV on cerebral ischemic-reperfusion
injury in rats and to explore underlying mechanisms of brain protection. Methods Sixty …

Background: Ischemia/reperfusion (I/R) caused by ischemic stroke treatments leads to brain
injury, and autophagy plays a role in the pathology. Astragaloside IV is a potential …

Abstract Astragaloside IV (AS-IV) is an active component extracted from the traditional
Chinese herbal medicine. AS-IV is a neuroprotective component in cerebral ischemic …

Astragaloside IV (AST‐IV) is a principal component of Radix Astragali seu Hedysari
(Huangqi) and exerts potential neuroprotection in experimental ischemic stroke. Here, we …

ETHNOPHARMACOLOGICAL RELEVANCE: Astragaloside IV and tetramethylpyrazine have
been extensively used in the cardio-cerbrovascular diseases of medicine as a chief …

Abstract Astragaloside IV (AS-IV) is the main active component isolated from the traditional
Chinese medicinal herb Astragalus membranaceus. Studies have demonstrated that AS-IV …

Ethnopharmacological relevance Apoptosis plays an important role in cerebral ischemia-
reperfusion injury and triggers a series of pathological changes which may even be life …

Objective To observe the effect of astragaloside IV on inflammatory factors and ultrastructure
in rats with cerebral ischemia reperfusion. Methods A cerebral ischemia reperfusion injury …

Our previous work has shown that activating PI3K/Akt/mTOR signaling pathway is involved
in angiogenesis after ischemic stroke, and recent studies have revealed that astragaloside …

Inflammation injury plays a key role in the process of cerebral injury induced by
ischemia/reperfusion (I/R). Thus, we studied the potential of astragaloside IV, one of the …