In antitumor immunity, dendritic cells (DCs) capture, process, and present tumor antigens to
T cells, initiating a tumoricidal response. However, DCs are often dysfunctional due to their …

ABSTRACT MicroRNA 155 (miR-155) plays important roles in the regulation of the
development and functions of a variety of immune cells. We previously revealed a vital role …

Evidence suggests that increased microRNA-155 (miR-155) expression in immune cells
enhances antitumor immune responses. However, given the reported association of miR …

Paracrine activation of cells contained in the tumor microenvironment promotes tumor
progression and metastasis. In breast cancer, malignant cells recruit and educate …

CD44 is closely linked to breast cancer progression; however, the regulatory functions of
microRNAs (miRs) in breast cancer have yet to be fully elucidated. In order to investigate the …

Immune cells in tumor microenvironment play a prominent role in tumor progression and
metastasis. MicroRNA‐155 (miR‐155) represents an important player in innate and adaptive …

T lymphocyte-mediated immune responses are critical for antitumour immunity; however, T
cell function is impaired in the tumour environment. MicroRNAs are involved in regulation of …

A productive immune response requires transient upregulation of the microRNA miR-155 in
hematopoietic cells mediating innate and adaptive immunity. In order to investigate miR-155 …

Abstract microRNAs are short noncoding RNAs that regulate protein expression
posttranscriptionally. We previously showed that miR-155 promotes effector CD8+ T-cell …

Tumor-associated macrophages (TAMs) play critical roles in promoting tumor progression
and invasion. However, the molecular mechanisms underlying TAM regulation remain to be …