Epigenetics involves the study of various modes of adaptable transcriptional regulation,
contributing to cell identity, characteristics, and function. During central nervous system …

Epigenetic modifications play a fundamental role in the regulation of cellular gene
expression. In addition to their role in mediating short-term responses, some epigenetic …

Innate immune cells have complex signalling pathways for sensing pathogens and initiating
innate immune responses against infection. These pathways are tightly regulated at different …

Epigenetics comprises various mechanisms that mold chromatin structures and regulate
gene expression with stability, thus defining cell identity and function and adapting cells to …

Immunity relies on the heterogeneity of immune cells and their ability to respond to pathogen
challenges. In the adaptive immune system, lymphocytes display a highly diverse antigen …

Epigenetics connects genetic and environmental factors: it includes DNA methylation,
histone post‐translational modifications and the regulation of chromatin accessibility by non …

The innate immune response is a rapid response to pathogens or danger signals. It is
precisely activated not only to efficiently eliminate pathogens but also to avoid excessive …

The interaction of innate immune cells with pathogens leads to changes in gene expression
that elicit our body's first line of defense against infection. Although signaling pathways and …

Highlights•Genetic factors contribute to host variation in innate immune responses, response
eQTL.•Epigenetic marks are dynamically remodeled in response to immune challenges.• …

Multidisciplinary approaches combining microbiology, cell biology, and genetics have
improved our understanding of bacterial diseases by elucidating mechanisms employed by …