Context Sentinel lymph node dissection (SLND) accurately identifies nodal metastasis of
early breast cancer, but it is not clear whether further nodal dissection affects survival …

Importance The results of the American College of Surgeons Oncology Group Z0011
(ACOSOG Z0011) trial were first reported in 2005 with a median follow-up of 6.3 years …

Background Trials evaluating the omission of completion axillary-lymph-node dissection in
patients with clinically node-negative breast cancer and sentinel-lymph-node metastases …

BACKGROUND. The role for completion axillary dissection (CLND) in patients with breast
cancer who have tumor‐positive sentinel lymph nodes (SLN) has been questioned. The …

Methods: ACOSOG Z0011 prospectively examined overall survival of patients with SLN
metastases undergoing breast-conserving therapy randomized to undergo ALND after …

Axillary dissection is the current standard of care for patients with breast cancer who are
diagnosed with metastasis to axillary sentinel lymph nodes (SLNs). Recently, that concept …

Hypothesis Sentinel node (SN) biopsy for breast cancer enhances staging sensitivity, often
demonstrating only micrometastases (< 2 mm) or isolated, keratin-positive cells. When SN …

Methods: American College of Surgeons Oncology Group Z0011 was a prospective trial
examining survival of patients with SN metastases detected by standard H and E, who were …

Purpose Patients with breast cancer metastasis to the sentinel lymph nodes (SLNs)
generally undergo completion axillary lymph node dissection (cALND), either concurrently …

Background In early breast cancer patients with sentinel node metastasis, the effect of
axillary lymph node dissection (ALND) is controversial. The purpose of this study is to …