[HTML][HTML] Clusterin is a biomarker of breast cancer prognosis and correlated with immune microenvironment

P Yang, Z Yang, Y Dong, L Yang, S Peng… - Translational Cancer …, 2023 - ncbi.nlm.nih.gov
Background It has been established that clusterin is involved in the invasion of immune cells
in the tumor microenvironment, but it remains unknown how it promotes immune invasion in …

Effects of clusterin over-expression on metastatic progression and therapy in breast cancer

L Flanagan, L Whyte, N Chatterjee, M Tenniswood - BMC cancer, 2010 - Springer
Background Clusterin is a secreted glycoprotein that is upregulated in a variety of cell lines
in response to stress, and enhances cell survival. A second nuclear isoform of clusterin that …

Stromal clusterin expression predicts therapeutic response to neoadjuvant chemotherapy in triple negative breast cancer

Y Wang, AS Brodsky, J Xiong, ML Lopresti, D Yang… - Clinical Breast …, 2018 - Elsevier
Background Expression of clusterin correlates with tumor progression and therapeutic
response in several human malignancies, including breast cancer. However, its predictive …

Clusterin overexpression and relapse-free survival in breast cancer

CK Yom, HY Woo, SY Min, SY Kang… - Anticancer research, 2009 - ar.iiarjournals.org
Background: The prognostic significance of the antiapoptotic protein secretory clusterin
overexpression in breast cancer is unclear. Patients and Methods: Secretory clusterin …

Overexpression of clusterin in human breast carcinoma

M Redondo, E Villar, J Torres-Munoz, T Tellez… - The American journal of …, 2000 - Elsevier
Clusterin has been implicated in numerous processes including active cell death, immune
regulation, cell adhesion and morphological transformation. The purpose of this study was to …

Prognostic significance of clusterin immunoreactivity in breast cancer.

S Krüger, V Ola, D Fischer, AC Feller, M Friedrich - Neoplasma, 2007 - europepmc.org
Clusterin (CLU) is involved in a variety of biological processes and has been found to be
expressed even in many human malignancies, including breast cancer. Currently, there are …

Cytoplasmic clusterin expression is associated with longer survival in patients with resected non–small cell lung cancer

JM Albert, A Gonzalez, PP Massion, H Chen… - … Biomarkers & Prevention, 2007 - AACR
Background: Clusterin is a glycoprotein that has been implicated in many processes,
including apoptosis, cell cycle regulation, and DNA repair. Previous studies have examined …

Clusterin: a potential target for improving response to antiestrogens

S Toffanin, MG Daidone, P Miodini… - International …, 2008 - spandidos-publications.com
Antiestrogens represent the first line of therapy in the treatment of estrogen receptor-positive
(ER+) breast cancer patients. Unfortunately, up to 40% of patients develop resistance …

Overexpression of clusterin in human hepatocellular carcinoma

YK Kang, SW Hong, H Lee, WH Kim - Human pathology, 2004 - Elsevier
Clusterin has been reported to play a significant role in tumorigenesis, and its
overexpression occurs in various human malignancies. We examine the clusterin …

Overexpression of clusterin in ovarian cancer is correlated with impaired survival

GF Yang, XM Li, D Xie - International Journal of Gynecologic Cancer, 2009 - ijgc.bmj.com
Clusterin has been found to be overexpressed in several human malignancies and also be
expressed in ovarian carcinoma tissues. However, to date, no study has investigated the …