Does neuroinflammation fan the flame in neurodegenerative diseases?
TC Frank-Cannon, LT Alto, FE McAlpine… - Molecular …, 2009 - Springer
While peripheral immune access to the central nervous system (CNS) is restricted and tightly
controlled, the CNS is capable of dynamic immune and inflammatory responses to a variety …
controlled, the CNS is capable of dynamic immune and inflammatory responses to a variety …
Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression
HM Gao, JS Hong - Trends in immunology, 2008 - cell.com
Neurodegenerative diseases are a group of chronic, progressive disorders characterized by
the gradual loss of neurons in discrete areas of the central nervous system (CNS). The …
the gradual loss of neurons in discrete areas of the central nervous system (CNS). The …
Mechanisms underlying inflammation in neurodegeneration
Inflammation is associated with many neurodegenerative diseases, including Alzheimer's
disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis. In this …
disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis. In this …
The benefits of neuroinflammation for the repair of the injured central nervous system
Inflammation of the nervous system (neuroinflammation) is now recognized as a hallmark of
virtually all neurological disorders. In neuroinflammatory conditions such as multiple …
virtually all neurological disorders. In neuroinflammatory conditions such as multiple …
Inflammation in the early stages of neurodegenerative pathology
PJ Khandelwal, AM Herman, CEH Moussa - Journal of neuroimmunology, 2011 - Elsevier
Inflammation is secondary to protein accumulation in neurodegenerative diseases, including
Alzheimer's, Parkinson's and Amyotrophic Lateral Sclerosis. Emerging evidence indicate …
Alzheimer's, Parkinson's and Amyotrophic Lateral Sclerosis. Emerging evidence indicate …
Microglia and neurodegeneration: the role of systemic inflammation
C Cunningham - Glia, 2013 - Wiley Online Library
It is well accepted that CNS inflammation has a role in the progression of chronic
neurodegenerative disease, although the mechanisms through which this occurs are still …
neurodegenerative disease, although the mechanisms through which this occurs are still …
Role of inflammation in neurodegenerative diseases
L Minghetti - Current opinion in neurology, 2005 - journals.lww.com
Although significant advances have been made in our knowledge of degenerative diseases,
there remains controversy regarding whether neuroinflammation and microglial activation …
there remains controversy regarding whether neuroinflammation and microglial activation …
Neuroinflammation: the devil is in the details
There is significant interest in understanding inflammatory responses within the brain and
spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are …
spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are …
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
HS Kwon, SH Koh - Translational neurodegeneration, 2020 - Springer
Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …
An inflammation-centric view of neurological disease: beyond the neuron
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …