Brain-derived neurotrophic factor in brain disorders: focus on neuroinflammation

B Lima Giacobbo, J Doorduin, HC Klein… - Molecular …, 2019 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates …

The role of brain-derived neurotrophic factor signaling in central nervous system disease pathogenesis

SH Dou, Y Cui, SM Huang, B Zhang - Frontiers in Human …, 2022 - frontiersin.org
Recent studies have found abnormal levels of brain-derived neurotrophic factor (BDNF) in a
variety of central nervous system (CNS) diseases (eg, stroke, depression, anxiety …

Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity

F Calabrese, AC Rossetti, G Racagni… - Frontiers in cellular …, 2014 - frontiersin.org
Cytokines are key regulatory mediators involved in the host response to immunological
challenges, but also play a critical role in the communication between the immune and the …

Cellular and molecular mechanisms of the brain-derived neurotrophic factor in physiological and pathological conditions

V Begni, MA Riva, A Cattaneo - Clinical Science, 2017 - portlandpress.com
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a key role in the
central nervous system, promoting synaptic plasticity, neurogenesis and neuroprotection …

Recent advances on the role of brain-derived neurotrophic factor (BDNF) in neurodegenerative diseases

KF Azman, R Zakaria - International journal of molecular sciences, 2022 - mdpi.com
Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are essential for neuronal
survival and growth. The signaling cascades initiated by BDNF and its receptor are the key …

Brain-derived neurotrophic factor and Alzheimer's disease: physiopathology and beyond

BS Diniz, AL Teixeira - Neuromolecular medicine, 2011 - Springer
Brain-derived neurotrophic factor (BDNF) is the most widely distributed neurotrophin in the
central nervous system where it plays several pivotal roles in synaptic plasticity and …

Brain-derived neurotropic factor in neurodegenerative disorders

AM Ibrahim, L Chauhan, A Bhardwaj, A Sharma… - Biomedicines, 2022 - mdpi.com
Globally, neurodegenerative diseases cause a significant degree of disability and distress.
Brain-derived neurotrophic factor (BDNF), primarily found in the brain, has a substantial role …

[HTML][HTML] Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain

M Miranda, JF Morici, MB Zanoni… - Frontiers in cellular …, 2019 - frontiersin.org
Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

Brain-derived neurotrophic factor as a drug target for CNS disorders

S Pezet, M Malcangio - Expert opinion on therapeutic targets, 2004 - Taylor & Francis
Brain-derived neurotrophic factor (BDNF) belongs to the neurotrophin family of trophic
factors. BDNF is widely and abundantly expressed in the CNS and is available to some …

BDNF therapeutic mechanisms in neuropsychiatric disorders

AH Bazzari, FH Bazzari - International Journal of Molecular Sciences, 2022 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is the most abundant neurotrophin in the adult
brain and functions as both a primary neurotrophic signal and a neuromodulator. It serves …