MicroRNAs as peripheral biomarkers in aging and age-related diseases

S Kumar, M Vijayan, JS Bhatti, PH Reddy - Progress in molecular biology …, 2017 - Elsevier
MicroRNAs (miRNAs) are found in the circulatory biofluids considering the important
molecules for biomarker study in aging and age-related diseases. Blood or blood …

Common diseases alter the physiological age-related blood microRNA profile

T Fehlmann, B Lehallier, N Schaum, O Hahn… - Nature …, 2020 - nature.com
Aging is a key risk factor for chronic diseases of the elderly. MicroRNAs regulate post-
transcriptional gene silencing through base-pair binding on their target mRNAs. We …

Circulating miRNAs in ageing and ageing-related diseases

HJ Jung, Y Suh - Journal of Genetics and Genomics, 2014 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression
at the post-transcriptional level. They are involved in important biological processes …

Circulating microRNAs in medicine

T Pozniak, D Shcharbin, M Bryszewska - International journal of …, 2022 - mdpi.com
Circulating microRNAs (c-microRNAs, c-miRNAs), which are present in almost all biological
fluids, are promising sensitive biomarkers for various diseases (oncological and …

Investigation of microRNA expression in human serum during the aging process

H Zhang, H Yang, C Zhang, Y Jing… - … Series A: Biomedical …, 2015 - academic.oup.com
Abstract Background. Although serum microRNAs (miRNAs) play essential roles in the
diagnosis of various diseases, little is known about circulating miRNAs in the aging process …

Circulating microRNAs as biomarkers in cancer diagnosis

MMH Sohel - Life sciences, 2020 - Elsevier
MicroRNAs (miRNAs) are a group of tiny molecules of 18–22 nucleotide long noncoding
RNA that regulate the post-transcriptional gene expression through translational inhibition …

MicroRNAs as biomarkers of disease onset

M Ciesla, K Skrzypek, M Kozakowska… - Analytical and …, 2011 - Springer
MicroRNAs (miRNAs) are small, noncoding RNA molecules with the ability to
posttranscriptionally regulate gene expression via targeting the 3′ untranslated region of …

[HTML][HTML] Circulating microRNAs as biomarkers in health and disease

VK Velu, R Ramesh, AR Srinivasan - Journal of clinical and …, 2012 - ncbi.nlm.nih.gov
In the recent years, circulating nucleic acids have emerged as new biomarkers. Among
these, microRNAs (miRNA) have evolved as promising and potential markers of both …

[HTML][HTML] Age-related changes in microRNA levels in serum

NN Hooten, M Fitzpatrick, WH Wood 3rd, S De… - Aging (Albany …, 2013 - ncbi.nlm.nih.gov
Abstract microRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally
regulate gene expression by targeting specific mRNAs. Altered expression of circulating …

microRNA in cardiovascular aging and age-related cardiovascular diseases

C de Lucia, K Komici, G Borghetti… - Frontiers in …, 2017 - frontiersin.org
Over the last decades, life expectancy has significantly increased although several chronic
diseases persist in the population, with aging as the leading risk factor. Despite …