[HTML][HTML] Astragaloside IV alleviates infarction induced cardiomyocyte injury by improving mitochondrial morphology and function
W Zhang, L Zhang, H Zhou, C Li, C Shao… - Frontiers in …, 2022 - frontiersin.org
The protective effect of astragaloside IV (AS-IV) on myocardial injury after myocardial
infarction has been reported. However, the underlying mechanism is still largely unknown …
infarction has been reported. However, the underlying mechanism is still largely unknown …
Astragaloside iv ameliorates hypoxia/reoxygenation injury via regulating mitochondrial homeostasis in rat cardiomyocytes.
AM Liu, YL Mou, ZW Xu, Q Liu - 2020 - cabidigitallibrary.org
This study was designed to investigate the effect and mechanism of astragaloside IV (ASIV)
on mitochondrial morphology and function of rat cardiomyocytes under …
on mitochondrial morphology and function of rat cardiomyocytes under …
Astragaloside IV protects heart from ischemia and reperfusion injury via energy regulation mechanisms
L Tu, CS Pan, XH Wei, L Yan, YY Liu, JY Fan… - …, 2013 - Wiley Online Library
Objective This study was designed to investigate the protective potential of AS‐IV against
ischemia and I/R‐induced myocardial damage, with focusing on possible involvement of …
ischemia and I/R‐induced myocardial damage, with focusing on possible involvement of …
[HTML][HTML] Effect of astragaloside IV against rat myocardial cell apoptosis induced by oxidative stress via mitochondrial ATP-sensitive potassium channels
FY Guan, SJ Yang, J Liu… - Molecular Medicine …, 2015 - spandidos-publications.com
Astragaloside is one of the most common traditional Chinese medicines and is derived from
Astragalus membranaceus. Astragaloside IV (AsIV) is a monomer located in an extract of …
Astragalus membranaceus. Astragaloside IV (AsIV) is a monomer located in an extract of …
[HTML][HTML] A single, acute astragaloside IV therapy protects cardiomyocyte through attenuating superoxide anion-mediated accumulation of autophagosomes in …
K Huang, Y Yu, S Liu, Y Zhou, J Wang… - Frontiers in …, 2021 - frontiersin.org
Myocardial ischemia-reperfusion (I/R) injury, characterized by myocardial cell death (eg,
apoptosis) and generation of reactive oxygen species (ROS) such as superoxide (O2·−) and …
apoptosis) and generation of reactive oxygen species (ROS) such as superoxide (O2·−) and …
[HTML][HTML] Astragaloside IV ameliorates myocardial infarction induced apoptosis and restores cardiac function
C Sun, G Zeng, T Wang, H Ren, H An, C Lian… - Frontiers in Cell and …, 2021 - frontiersin.org
Background Type 2 diabetes mellitus increases the risk of cardiovascular disease including
myocardial infarction (MI). Inflammation and apoptosis have been implicated in the …
myocardial infarction (MI). Inflammation and apoptosis have been implicated in the …
[HTML][HTML] A preclinical systematic review and meta-analysis of astragaloside IV for myocardial ischemia/reperfusion injury
Q Zheng, JZ Zhu, XY Bao, PC Zhu, Q Tong… - Frontiers in …, 2018 - frontiersin.org
Astragaloside IV (AS-IV), the major pharmacological extract from Astragalus membranaceus
Bunge, possesses a variety of biological activities in the cardiovascular systems. Here, we …
Bunge, possesses a variety of biological activities in the cardiovascular systems. Here, we …
[HTML][HTML] Astragaloside IV protects rat cardiomyocytes from hypoxia-induced injury by down-regulation of miR-23a and miR-92a
L Gong, H Chang, J Zhang, G Guo, J Shi… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Astragaloside IV (AS-IV), a traditional Chinese medicine isolated from
Astragalus membranaceus, has been shown to exert cardioprotective effect previously. This …
Astragalus membranaceus, has been shown to exert cardioprotective effect previously. This …
Astragaloside IV attenuates myocardial ischemia/reperfusion injury in rats via inhibition of calcium-sensing receptor-mediated apoptotic signaling pathways
B Yin, X Hou, M Lu - Acta Pharmacologica Sinica, 2019 - nature.com
Astragaloside IV (AsIV) is an active saponin extracted from Astragalus membranaceus,
which has shown cardioprotective effects in a number of experimental animals. In this study …
which has shown cardioprotective effects in a number of experimental animals. In this study …
[HTML][HTML] Beneficial effects of astragaloside IV against angiotensin II-induced mitochondrial dysfunction in rat vascular smooth muscle cells
Y Lu, S Li, H Wu, Z Bian, J Xu… - International …, 2015 - spandidos-publications.com
Abstract Angiotensin II (Ang II)-induced mitochondrial dysfunction is a prominent
characteristic of the majority of cardiovascular diseases. Astragaloside IV (As-IV), the major …
characteristic of the majority of cardiovascular diseases. Astragaloside IV (As-IV), the major …