The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disorders
A Didonna, P Opal - Molecular neurodegeneration, 2019 - Springer
Many neurodegenerative disorders, including Parkinson's, Alzheimer's, and amyotrophic
lateral sclerosis, are well known to involve the accumulation of disease-specific proteins …
lateral sclerosis, are well known to involve the accumulation of disease-specific proteins …
Neurofilaments in health and disease
JP Julien, WE Mushynski - Progress in nucleic acid research and molecular …, 1998 - Elsevier
This article reviews current knowledge of neurofilament structure, phosphorylation, and
function and neurofilament involvement in disease. Neurofilaments are obligate …
function and neurofilament involvement in disease. Neurofilaments are obligate …
Neuronal intermediate filaments: new progress on an an old subject
Z Xu, DLY Dong, DW Cleveland - Current Opinion in Neurobiology, 1994 - Elsevier
Neurofilaments (NFs) are the major intermediate filaments in most mature neurons. Genetic
approaches have now proven that NFs are an essential determinant for radial growth of …
approaches have now proven that NFs are an essential determinant for radial growth of …
Functions of intermediate filaments in neuronal development and disease
RC Lariviere, JP Julien - Journal of neurobiology, 2004 - Wiley Online Library
Five major types of intermediate filament (IF) proteins are expressed in mature neurons: the
three neurofilament proteins (NF‐L, NF‐M, and NF‐H), α‐internexin, and peripherin. While …
three neurofilament proteins (NF‐L, NF‐M, and NF‐H), α‐internexin, and peripherin. While …
[HTML][HTML] Neurofilamentopathy in neurodegenerative diseases
Q Liu, F Xie, A Alvarado-Diaz, MA Smith… - The open neurology …, 2011 - ncbi.nlm.nih.gov
Neurofilament protein alterations are found in many neurodegenerative diseases, such as
amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal …
amyotrophic lateral sclerosis, Parkinson, Alzheimer, and Charcot-Marie-Tooth. Abnormal …
Neurofilaments and neurofilament proteins in health and disease
Neurofilaments (NFs) are unique among tissue-specific classes of intermediate filaments
(IFs) in being heteropolymers composed of four subunits (NF-L [neurofilament light]; NF-M …
(IFs) in being heteropolymers composed of four subunits (NF-L [neurofilament light]; NF-M …
Review of the multiple aspects of neurofilament functions, and their possible contribution to neurodegeneration
R Perrot, R Berges, A Bocquet, J Eyer - Molecular neurobiology, 2008 - Springer
Neurofilaments (NF) are the most abundant cytoskeletal component of large myelinated
axons from adult central and peripheral nervous system. Here, we provide an overview of …
axons from adult central and peripheral nervous system. Here, we provide an overview of …
Specialized roles of neurofilament proteins in synapses: Relevance to neuropsychiatric disorders
Neurofilaments are uniquely complex among classes of intermediate filaments in being
composed of four subunits (NFL, NFM, NFH and alpha-internexin in the CNS) that differ in …
composed of four subunits (NFL, NFM, NFH and alpha-internexin in the CNS) that differ in …
Neuronal intermediate filaments and neurodegenerative disorders
R Perrot, J Eyer - Brain research bulletin, 2009 - Elsevier
Intermediate filaments represent the most abundant cytoskeletal element in mature neurons.
Mutations and/or accumulations of neuronal intermediate filament proteins are frequently …
Mutations and/or accumulations of neuronal intermediate filament proteins are frequently …
Neuronal intermediate filaments.
MK Lee, DW Cleveland - Annual review of neuroscience, 1996 - europepmc.org
Neurofilaments (NFs) are the most abundant structural components in large-diameter
myelinated axons. Assembled as obligate heteropolymers requiring NF-L and …
myelinated axons. Assembled as obligate heteropolymers requiring NF-L and …