Membrane fusion is a key process in all living organisms that contributes to a variety of
biological processes including viral infection, cell fertilization, as well as intracellular …

Eukaryotes have a remarkably well-conserved apparatus for the trafficking of proteins
between intracellular compartments and delivery to their target organelles. This apparatus …

During neuronal exocytosis, the vesicle-bound soluble NSF attachment protein (SNAP)
receptor (SNARE) synaptobrevin 2 forms complexes with the plasma membrane–bound …

In eukaryotes, most intracellular membrane fusion reactions are mediated by the interaction
of SNARE proteins that are present in both fusing membranes. However, the minimal …

Synaptic vesicle fusion during neurotransmitter release is mediated by assembly of SNARE-
and SM-protein complexes composed of syntaxin-1, SNAP-25, synaptobrevin-2/VAMP2, and …

SNARE proteins are essential for different types of intracellular membrane fusion. Whereas
interaction between their cytoplasmic domains is held responsible for establishing …

SNARE molecules are the core constituents of the protein machinery that facilitate fusion of
synaptic vesicles with the presynaptic plasma membrane, resulting in the release of …

The pairing of cognate v-and t-SNAREs between two opposing lipid bilayers drives
spontaneous membrane fusion and confers specificity to intracellular membrane trafficking …

SNARE proteins play a central role in nearly all intracellular fusion reactions; fusion is
thermodynamically driven by formation of trans-SNARE complexes (SNAREpins) through …

Soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) proteins have
been at the fore-front of research on biological membrane fusion for some time. The …