NMR-based conformational analysis of sphingomyelin in bicelles

T Yamaguchi, T Suzuki, T Yasuda, T Oishi… - Bioorganic & medicinal …, 2012 - Elsevier
Sphingomyelin (SM) is a common sphingolipid in mammalian membranes and is known to
be substantially involved in cellular events such as the formation of lipid rafts. Despite its …

[PDF][PDF] Orientation and order of the amide group of sphingomyelin in bilayers determined by solid-state NMR

N Matsumori, T Yamaguchi, Y Maeta, M Murata - Biophysical Journal, 2015 - cell.com
Sphingomyelin (SM) and cholesterol (Chol) are considered essential for the formation of
lipid rafts; however, the types of molecular interactions involved in this process, such as …

[PDF][PDF] Cholesterol-induced conformational change in the sphingomyelin headgroup

S Hanashima, K Murakami, M Yura, Y Yano… - Biophysical …, 2019 - cell.com
Sphingomyelin (SM) and cholesterol (Cho) are the important lipids for the formation of
biologically functional membrane domains, lipid rafts. However, the interaction between Cho …

[PDF][PDF] Importance of the sphingosine base double-bond geometry for the structural and thermodynamic properties of sphingomyelin bilayers

L Janosi, A Gorfe - Biophysical journal, 2010 - cell.com
The precise role of the sphingosine base trans double bond for the unique properties of
sphingomyelins (SMs), one of the main lipid components in raftlike structures of biological …

Effects of chemical modification of sphingomyelin ammonium group on formation of liquid-ordered phase

SA Goretta, M Kinoshita, S Mori, H Tsuchikawa… - Bioorganic & medicinal …, 2012 - Elsevier
Sphingomyelin (SM) and cholesterol form microdomains called lipid rafts in cellular
membranes. To develop a versatile fluorescent lipid probe, chemical modifications to both …

[PDF][PDF] Sphingomyelin stereoisomers reveal that homophilic interactions cause nanodomain formation

Y Yano, S Hanashima, T Yasuda, H Tsuchikawa… - Biophysical journal, 2018 - cell.com
Sphingomyelin is an abundant lipid in some cellular membrane domains, such as lipid rafts.
Hydrogen bonding and hydrophobic interactions of the lipid with surrounding components …

[PDF][PDF] Effect of sphingomyelin headgroup size on molecular properties and interactions with cholesterol

A Björkbom, T Róg, K Kaszuba, M Kurita… - Biophysical journal, 2010 - cell.com
Sphingomyelins (SMs) and sterols are important constituents of the plasma membrane and
have also been identified as major lipid components in membrane rafts. Using SM analogs …

[PDF][PDF] Detection of sphingomyelin clusters by raman spectroscopy

K Shirota, K Yagi, T Inaba, PC Li, M Murata, Y Sugita… - Biophysical journal, 2016 - cell.com
Sphingomyelin (SM) is a major sphingolipid in mammalian cells that forms specific lipid
domains in combination with cholesterol (Chol). Using molecular-dynamics simulation and …

[HTML][HTML] Structural characterization of N-lignoceroyl (C24: 0) sphingomyelin bilayer membranes: a re-evaluation

H Takahashi, T Hayakawa, Y Kawasaki, K Ito… - Applied …, 2007 - journals.iucr.org
Sphingomyelin (SM) is a membrane lipid and plays important roles in signaling, protein
trafficking, cell growth and death. The structure of the bilayer of a hydrated highly asymmetric …

Molecular properties of various structurally defined sphingomyelins–correlation of structure with function

PJ Slotte - Progress in lipid research, 2013 - Elsevier
Sphingomyelins are important phospholipids in plasma membranes of most cells. Because
of their dominantly saturated nature, they affect the lateral structure of membranes, and …