C-reactive protein: structure, function, regulation, and role in clinical diseases

HH Zhou, YL Tang, TH Xu, B Cheng - Frontiers in Immunology, 2024 - frontiersin.org
C-reactive protein (CRP) is a plasma protein that is evolutionarily conserved, found in both
vertebrates and many invertebrates. It is a member of the pentraxin superfamily …

C-reactive protein and its structural isoforms: an evolutionary conserved marker and central player in inflammatory diseases and beyond

JD McFadyen, J Zeller, LA Potempa… - … , lipoproteins and other …, 2020 - Springer
C-reactive protein (CRP) is an evolutionary highly conserved member of the pentraxin
superfamily of proteins. CRP is widely used as a marker of inflammation, infection and for …

Regulation of conformational changes in C-reactive protein alters its bioactivity

N Ullah, Y Wu - Cell biochemistry and biophysics, 2022 - Springer
The acute phase C-reactive protein (CRP) is mainly synthesized and secreted by the liver in
a cytokine-mediated response to infection or inflammation and circulates as a pentamer …

Dissociation of C-reactive protein localizes and amplifies inflammation: evidence for a direct biological role of C-reactive protein and its conformational changes

JD McFadyen, J Kiefer, D Braig, J Loseff-Silver… - Frontiers in …, 2018 - frontiersin.org
C-reactive protein (CRP) is a member of the pentraxin superfamily that is widely recognized
as a marker of inflammatory reactions and cardiovascular risk in humans. Recently, a …

C-reactive protein: an activator of innate immunity and a modulator of adaptive immunity

TW Du Clos, C Mold - Immunologic research, 2004 - Springer
C-reactive protein (CRP) is an acute-phase serum protein and a member of the pentraxin
protein family. Its host defense functions predate the adaptive immune system by millions of …

C-reactive protein: the most familiar stranger

SR Ji, SH Zhang, Y Chang, HY Li, MY Wang… - The Journal of …, 2023 - journals.aai.org
C-reactive protein (CRP) is a highly conserved pentraxin with pattern recognition receptor–
like activities. However, despite being used widely as a clinical marker of inflammation, the …

CRP: historical perspective, structure, evolution, synthesis, clinical and biological functions

W Ansar, S Ghosh, W Ansar, S Ghosh - Biology of C Reactive Protein in …, 2016 - Springer
The C-reactive protein (CRP) is a plasma protein belonging to pentraxin family and has
hepatic origin. It is the chief component of any inflammatory reaction. A key mediator of the …

C-reactive protein: An inflammatory marker with specific role in physiology, pathology, and diagnosis

S Chandrashekara - Internet Journal of Rheumatology and …, 2014 - chanrejournals.com
C-reactive protein (CRP), an acute phase protein belonging to pentraxin family of proteins,
increases 1000-fold or more in concentration in blood during the occurrence of an injury …

[图书][B] Biology of C reactive protein in health and disease

W Ansar, S Ghosh - 2016 - Springer
This book offers a comprehensive study of C-reactive protein (CRP) belonging to the
pentraxin family, including a brief history of CRP, its structure, synthesis and evolution …

C-reactive protein and the biology of disease

W Ansar, S Ghosh - Immunologic research, 2013 - Springer
The C-reactive protein (CRP) is a plasma protein of hepatic origin, belonging to pentraxin
family and forms a major component of any inflammatory reaction. A key component of the …