Altered RNA editing has been linked to several neurodevelopmental disorders, including
autism spectrum disorder (ASD) and intellectual disability, in addition to depression …

Adenosine deaminase acting on RNA 2 (ADAR2) is an important enzyme involved in RNA
editing processes, particularly in the conversion of adenosine to inosine in RNA molecules …

Adenosine deaminases acting on RNA 1 (ADAR1) are enzymes involved in editing
adenosine to inosine in the dsRNAs of cells associated with cancer development. The p150 …

Background Alzheimer's disease (AD), the most common cause of dementia in the elderly, is
a progressive neurodegenerative disorder that gradually affects cognitive function and …

Alzheimer's disease (AD) is a neurological ailment that affects the elderly, causes dementia
and cognitive impairment. The disease's specific mechanism has yet to be uncovered. New …

This study has investigated docking-based 2D-and 3D-quantitative structure-activity
relationships (QSARs) for a range of 53 hydroxybenzamide analogues as anti-Human …

Histone deacetylases (HDACs) play a significant role in the epigenetic mechanism by
catalyzing deacetylation of lysine on histone in both animals and plants. HDACs involved in …

Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
that have emerged as among the serious health problems of the 21st century. The …

AIDS is one of the multifaceted diseases and this underlying complexity hampers its
complete cure. The toxicity of existing drugs and emergence of multidrug-resistant virus …

Acetylcholinesterase (AChE) inhibitors are currently in focus for the pharmacotherapy of
Alzheimer's disease (AD). These inhibitors increase the level of acetylcholine in the brain …