Clinical trials for progressive differentiated thyroid cancer: patient selection, study design, and recent advances

M Schlumberger, SI Sherman - Thyroid, 2009 - liebertpub.com
Treatment of metastatic differentiated thyroid cancer is first based on the use of radioiodine
and thyrotropin-suppressive thyroid hormone treatment. The recent availability of molecular …

Molecular targeted therapies for patients with refractory thyroid cancer

C Chougnet, M Brassard, S Leboulleux, E Baudin… - Clinical Oncology, 2010 - Elsevier
The recent availability of molecular targeted therapies leads to reconsideration of the
treatment strategy in patients with distant metastases from differentiated thyroid carcinoma …

New therapeutic approaches for metastatic thyroid carcinoma

E Baudin, M Schlumberger - The lancet oncology, 2007 - thelancet.com
Treatment of metastatic differentiated thyroid cancer (DTC) includes the use of radioiodine
and suppressive thyroid hormone treatment. A third of patients with distant metastases (who …

[HTML][HTML] Optimizing therapy for radioactive iodine-refractory differentiated thyroid cancer: current state of the art and future directions

R Dadu, ME Cabanillas - Minerva endocrinologica, 2012 - ncbi.nlm.nih.gov
The majority of patients with differentiated thyroid cancer are cured with standard primary
treatments including surgery, radioactive iodine and TSH suppression. A small proportion of …

[PDF][PDF] New therapeutic advances in the management of progressive thyroid cancer

JA Woyach, MH Shah - Endocrine-related cancer, 2009 - Citeseer
The spectrum of thyroid cancers ranges from one of the most indolent to one of the most
aggressive solid tumors identified. Conventional therapies for thyroid cancers are based on …

Evolving approaches to patients with advanced differentiated thyroid cancer

BR Haugen, SI Sherman - Endocrine reviews, 2013 - academic.oup.com
Advanced differentiated thyroid cancer (DTC), defined by clinical characteristics including
gross extrathyroidal invasion, distant metastases, radioiodine (RAI) resistance, and avidity …

[HTML][HTML] New approaches in the management of radioiodine-refractory thyroid cancer: the molecular targeted therapy era

J Capdevila, G Argiles… - Discovery …, 2010 - discoverymedicine.com
Although thyroid carcinoma usually has an excellent prognosis, the lack of therapeutic
options is an issue for patients that develop metastases and are resistant to radioiodine …

[HTML][HTML] New approaches for patients with advanced radioiodine-refractory thyroid cancer

F Pitoia, F Jerkovich, P Trimboli… - World Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
The cumulative evidence over the past decades has shown that the incidence of
differentiated thyroid carcinoma (DTC) has exponentially increased. Approximately 10% of …

Novel drug treatments of progressive radioiodine-refractory differentiated thyroid cancer

SP Weitzman, SI Sherman - Endocrinology and Metabolism …, 2019 - endo.theclinics.com
Most patients treated for differentiated thyroid cancer (DTC) fare quite well. Data from the
Surveillance, Epidemiology, and End Results (SEER) program show that 98.1% of patients …

Differentiated thyroid cancer—treatment: state of the art

B Schmidbauer, K Menhart, D Hellwig… - International journal of …, 2017 - mdpi.com
Differentiated thyroid cancer (DTC) is a rare malignant disease, although its incidence has
increased over the last few decades. It derives from follicular thyroid cells. Generally …