). It may also contribute to immobilization of mammalian transposons, suppression of
transcriptional noise, and the control of tissue-specific gene expression, but decisive …

DNA methylation is an epigenetic modification which plays an important role in chromatin
organization and gene expression. DNA methylation can silence genes and repetitive …

It has been nearly 40 y since it was suggested that genomic methylation patterns could be
transmitted via maintenance methylation during S phase and might play a role in the …

DNA methylation and chromatin modification operate along a common pathway to repress
transcription; accordingly, several experiments demonstrate that the effects of DNA …

DNA methylation has an essential regulatory function in mammalian development, serving
to repress nontranscribed genes stably in differentiated adult somatic cells. Recent data …

Epigenetic gene silencing results from the inhibition of transcription or from
posttranscriptional RNA degradation. DNA methylation is one of the most central and …

DNA methylation is a type of epigenetic marking that strongly influences chromatin structure
and gene expression in plants and mammals. Over the past decade, DNA methylation has …

Differentiation-related DNA methylation is receiving increasing attention, partly owing to
new, whole-genome analyses. These revealed that cell type-specific differential methylation …

Genes constitute only a small proportion of the total mammalian genome, and the precise
control of their expression in the presence of an overwhelming background of noncoding …

Genetic, biochemical and cytological studies on DNA methylation in several eukaryotic
organisms have resulted in leaps of understanding in the past three years. Discoveries of …