[HTML][HTML] Recent advances in endogenous neural stem/progenitor cell manipulation for spinal cord injury repair

J Li, W Luo, C Xiao, J Zhao, C Xiang, W Liu, R Gu - Theranostics, 2023 - ncbi.nlm.nih.gov
Traumatic spinal cord injury (SCI) can cause severe neurological impairments. Clinically
available treatments are quite limited, with unsatisfactory remediation effects. Residing …

Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances

SM Hosseini, B Borys, S Karimi-Abdolrezaee - Brain, 2024 - academic.oup.com
Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

Regulating endogenous neural stem cell activation to promote spinal cord injury repair

EAB Gilbert, N Lakshman, KSK Lau, CM Morshead - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) affects millions of individuals worldwide. Currently, there is no cure,
and treatment options to promote neural recovery are limited. An innovative approach to …

Current concepts of neural stem/progenitor cell therapy for chronic spinal cord injury

H Suzuki, Y Imajo, M Funaba, N Nishida… - Frontiers in Cellular …, 2022 - frontiersin.org
Chronic spinal cord injury (SCI) is a devastating condition that results in major neurological
deficits and social burden. It continues to be managed symptomatically, and no real …

Direct neuronal differentiation of neural stem cells for spinal cord injury repair

W Xue, C Fan, B Chen, Y Zhao, Z Xiao, J Dai - Stem Cells, 2021 - academic.oup.com
Spinal cord injury (SCI) typically results in long-lasting functional deficits, largely due to
primary and secondary wh ite matter damage at the site of injury. The transplantation of …

Therapeutic potential of induced neural stem cells for spinal cord injury

JY Hong, SH Lee, SC Lee, JW Kim, KP Kim… - Journal of Biological …, 2014 - ASBMB
The spinal cord does not spontaneously regenerate, and treatment that ensures functional
recovery after spinal cord injury (SCI) is still not available. Recently, fibroblasts have been …

The roles and applications of neural stem cells in spinal cord injury repair

W Guo, X Zhang, J Zhai, J Xue - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Spinal cord injury (SCI), which has no current cure, places a severe burden on patients.
Stem cell-based therapies are considered promising in attempts to repair injured spinal …

Human spinal oligodendrogenic neural progenitor cells enhance pathophysiological outcomes and functional recovery in a clinically relevant cervical spinal cord …

K Pieczonka, H Nakashima, N Nagoshi… - Stem Cells …, 2023 - academic.oup.com
Traumatic spinal cord injury (SCI) results in the loss of neurons, oligodendrocytes, and
astrocytes. Present interventions for SCI include decompressive surgery, anti-inflammatory …

The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury

CS Ahuja, A Mothe, M Khazaei… - Stem cells …, 2020 - academic.oup.com
Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …

Review of transplantation of neural stem/progenitor cells for spinal cord injury

AJ Mothe, CH Tator - International Journal of Developmental Neuroscience, 2013 - Elsevier
Spinal cord injury (SCI) is a debilitating condition often resulting in paralysis, yet currently
there is no effective treatment. Stem cell transplantation is a promising therapeutic strategy …